Search for dissertations about: "Antiviral Agents analysis"

Found 5 swedish dissertations containing the words Antiviral Agents analysis.

  1. 1. Adenovirus-host interactions : implications for tropism and therapy

    Author : Annasara Lenman; Niklas Arnberg; Lennart Svensson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenoviridae; Amino Acids; Antiviral Agents; Epithelial Cells; Factor IX;

    Abstract : Human adenoviruses (HAdVs) are common viruses often associated withgastrointestinal, ocular and respiratory infections. They can infect a widevariety of cells, both dividing and non-dividing. HAdVs attach to and infecttarget cells through interactions with cellular receptors. READ MORE

  2. 2. Interaction of herpes simplex virus with cell surface glycosaminoglycans as a target for antiviral intervention

    Author : Kicki Bergefall; Göteborgs universitet; []
    Keywords : HSV; glycoproteins; glycosaminoglycans; virus receptor; antiviral drugs;

    Abstract : Herpes simplex virus (HSV) infections in humans are predominantly manifested as oral cold sores or genital ulcers. As HSV infects cells by interaction with cell surface heparan sulfate (HS) and/or chondroitin sulfate (CS), the aim of the research work presented in this thesis was to explore the possibility of antiviral intervention with compounds that mimic HS or CS. READ MORE

  3. 3. The glycobiology of human adenovirus infections : implications for tropism and treatment

    Author : Naresh Chandra; Niklas Arnberg; Lars Frängsmyr; Gunnel Haldén; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; denovirus; cellular receptor; glycosaminoglycan; sialic acid; decoy receptors; tropism; epidemic keratoconjunctivitis; antiviral drugs; GAG-mimetic; obesity; medicinsk virologi; Medical Virology;

    Abstract : Human adenoviruses (HAdVs) are common human pathogens, causing gastrointestinal, ocular, and respiratory infections on a regular basis. Epidemic keratoconjunctivitis (EKC) is a severe ocular infection for which no approved antivirals are available. READ MORE

  4. 4. Bell's Palsy - Medical Treatment and Influence of Prognostic Factors

    Author : Sara Axelsson; Lund näs- och halssjukdomar Öron-; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bell’s palsy; Treatment; Recovery; Prognostic factors; Prednisolone; Valaciclovir; Facial grading; Sunnybrook;

    Abstract : Bell’s palsy is an acute onset of peripheral facial nerve dysfunction. Despite extensive research the aetiology is unclear. The most prevailing theory is that reactivation of viruses such as Herpes simplex type-1 or Varicella zoster may cause Bell’s palsy. READ MORE

  5. 5. Early host cell interactions and antivirals against ocular adenoviruses

    Author : Rickard Storm; Niklas Arnberg; Saw See Hong; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; Virus host interactions; Antivirals; Sialic acid; Integrins; Epidemic keratoconjuntivitis;

    Abstract : Viruses are common causative agents of ocular infection among humans. Epidemic keratoconjuntivitis (EKC) is a severe and contagious ocular disease with reported outbreaks worldwide. It is estimated that this disease affects 20-40 million individuals every year, which leads to huge socioeconomic costs for the affected countries. READ MORE