Search for dissertations about: "Anya Polischouk"

Found 1 swedish dissertation containing the words Anya Polischouk.

  1. 1. Molecular factors relevant to the radiosensitivity of human tumours

    University dissertation from Stockholm : Karolinska Institutet, Department of Oncology-Pathology

    Author : Anya Polischouk; Karolinska Institutet.; Karolinska Institutet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; c-Ha-ras; c-myc; radiosensitivity; DNA double-strand break repair; DNA singlestrand repair;

    Abstract : Oncogenes, activated copies of normal cellular genes, are involved in carcinogenesis and have been suggested to be determinants of cellular radiosensitivity (RS). Mutations and gene rearrangement of c-Ha-RAS and c-MYC oncogenes were analysed in 70 biopsies and 51 blood samples from the same patients and compared with RS estimated by the clinical tumour response and by response to irradiation of tumour samples using subrenal capsule assay. READ MORE