Search for dissertations about: "Apicomplexa"

Showing result 1 - 5 of 6 swedish dissertations containing the word Apicomplexa.

  2. 1. Environmental sequencing to infer patterns of eukaryotic evolution : Combining long-read and short-read metabarcoding

    Author : Mahwash Jamy; Fabien Burki; Micah Dunthorn; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protists; eukaryotes; environmental sequencing; ribosomal DNA; PacBio; long-read metabarcoding; phylogenetics; salt barrier; habitat evolution; eukaryotes evolution; evolutionary rate; Apicomplexa; pathogen; Biology with specialization in Systematics; Biologi med inriktning mot systematik;

    Abstract : Our view of eukaryotes is biased towards plants, animals, and fungi. But the vast majority of eukaryotic diversity is microbial in nature. These microbial eukaryotes are key players in all ecosystems on earth and are collectively known as protists. READ MORE

  4. 2. Host-parasite interactions in the dissemination of Toxoplasma gondii

    Author : Sachie Kanatani; Antonio Barragan; Per Uhlén; Isabelle Tardieux; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Apicomplexa; dendritic cells; microglia; cell migration; 14-3-3 proteins; GABAergic signaling; voltage-dependent calcium channel; host-parasite interaction; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Toxoplasma gondii is an obligate intracellular parasite that infects virtually all warm-blooded organisms. Systemic dissemination of T. gondii in the organism can cause life-threatening infection that manifests as Toxoplasma encephalitis in immune-compromised patients. READ MORE

  5. 3. Signaling determinants in Trojan horse-mediated dissemination of Toxoplasma gondii

    Author : Einar B. Ólafsson; Antonio Barragan; Eva Frickel; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apicomplexa; leukocyte motility; dendritic cell; amoeboid migration; host-parasite interactions; podosome; integrin; ITGB1; ECM; MAT; TIMP; MMP; MAPK; Erk; RTK; HGFR; Ras; calcium; VDCC; VGCC; calmodulin; CaMkII; CD63; FAK; SRC; Pi3k; hypermigration; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Toxoplasma gondii is an obligate intracellular parasite that infects all warm-blooded vertebrates including one third of the global human population. While infection is typically asymptomatic in healthy human hosts, reactivated and acute infection in immunosuppressed or immunecompromised individuals can lead to lethal toxoplasmic encephalitis After ingestion, the parasite crosses the intestinal epithelium and rapidly achieves systemic dissemination, ultimately establishing chronic infection in the brain. READ MORE

  6. 4. Transmigration of Toxoplasma gondii across biological barriers

    Author : Emily C. Ross; Antonio Barragan; Ildiko Rita Dunay; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Apicomplexa; blood-brain barrier; leukocyte; immune cell; transendothelial migration; cell adhesion molecule; host-pathogen; FAK; integrin; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Toxoplasma gondii is an obligate intracellular parasite that can likely infect all warm-blooded vertebrates, with estimates of up to 30% of the global human population being infected. Although infection with T. gondii is usually asymptomatic or mild, in immunocompromised individuals infection can lead to lethal toxoplasmic encephalitis. READ MORE

  7. 5. Modulation of mononuclear phagocyte function in the dissemination of Toxoplasma gondii

    Author : Arne L. ten Hoeve; Antonio Barragan; Nicolas Blanchard; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apicomplexa; dendritic cell; macrophage; intracellular signaling; parasite-derived effector protein; chemotaxis; leukocyte migration; transcription factor; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Toxoplasma gondii is an obligate intracellular Apicomplexan parasite that could possibly infect all warm-blooded animals. Acute infections with T. READ MORE