Search for dissertations about: "Apoptosis Inducing Factor activity"

Showing result 1 - 5 of 32 swedish dissertations containing the words Apoptosis Inducing Factor activity.

2. 1. Caspase-dependent and caspase-independent neuronal injury in the developing brain

   Author : Changlian Zhu; Göteborgs universitet; []
   Keywords : hypoxia ischemia; neonatal; cell death; caspase; apoptosis-inducing factor; brain; apoptosis; autophagy; nitric oxide;

   Abstract : Aims: To investigate the mechanisms of neuronal cell death after hypoxia-ischemia in the developing brain.Methods: Rats or mice were subjected to left common carotid artery ligation plus hypoxia. Animals were sacrificed at certain time points after hypoxia-ischemia. READ MORE

4. 2. Regulation of apoptosis in the thyroid epithelium

   Author : Abeba Demelash; Göteborgs universitet; []
   Keywords : Thyroid; Apoptosis; Caspase; Calpain; Hydrogen peroxide; TGF-beta; Staurosporine; Selenium; Cytochrome c;

   Abstract : Apoptosis or programmed cell death allows the multicellular organism to remove cells that are in excess or potentially dangerous. Apoptosis has to be strictly controlled, yet inappropriately activated or suppressed apoptototic may contribute to a variety of diseases, including cancer, autoimmune disorders and neurodegenerative conditions. READ MORE

5. 3. Caspase activation in human neuroblastoma cells: mechanisms and spatiotemporal aspects

   Author : Elena V. Ivanova; Kerstin Iverfeldt; Boris Zhivotovsky; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; apoptosis; caspase; local caspase activation; neurodegeneration; tau-anchored FRET sensors; tAFS; cancer; neuroblastoma; TNF-related apoptosis inducing ligand; TRAIL; protein kinase C; PKC; X-linked inhibitor of apoptosis protein; XIAP; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Abstract : Apoptosis is one of the modes of programmed cell death, in which several members of the caspase family of proteases play the central role. However, activation of apoptotic caspases does not necessarily lead to cell death. READ MORE

6. 4. Novel Interactors of X-linked Inhibitor of Apoptosis Protein : Expression and Effects on Tumor Cell Death

   Author : Håkan Steen; Dan Lindholm; Bertrand Joseph; Uppsala universitet; []
   Keywords : Neurobiology; XIAP; tumor cell death; apoptosis; caspases; basic helix-loop-helix protein; Neurobiologi;

   Abstract : Programmed cell death, or apoptosis, has during the last decade received a lot of attention due to its involvement in a large number of pathological conditions. Since death is always irreversible, it is important for cells to fully control the initiation and execution of this process. READ MORE

7. 5. Apoptosis induced by a human milk protein complex. Cellular and structural studies in tumour cells and bacteria

   Author : Anders Håkansson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; nuclear uptake; caspases; mitochondria; S. pneumoniae; alpha-lactalbumin; milk; breast-feeding; Apoptosis; tumour cells; transplantation; Immunologi; serologi;

   Abstract : Human milk contains a vast array of bioactive molecules, with nutritional and protective functions. This thesis describes the effects of a human milk protein complex, MAL, on tumour cells and bacteria. During our studies on the anti-adhesive properties of human milk we observed that a milk fraction killed tumour cells. READ MORE