Search for dissertations about: "Apoptosis physiology"

Showing result 1 - 5 of 36 swedish dissertations containing the words Apoptosis physiology.

2. 1. Studies on the Role of Apoptosis in Kidney Diseases

   Author : Linnéa Nilsson; Hjalmar Brismar; Anita Aperia; Lena Scott; Fredrik Palm; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apoptosis; diabetic kidney disease; hyperglycemia; mesangial cells; microscopy; ouabain; podocytes; proximal tubule cells; RNA-seq; SGLT; Apoptos; diabetisk njursjukdom; hyperglykemi; mesangiala celler; mikroskopi; ouabain; podocyter; proximala tubuli celler; RNA-seq; SGLT; Biological Physics; Biologisk fysik;

   Abstract : Apoptosis is one of the most common types of cell death. Under physiological conditions, it plays an essential role in removal of damaged and potentially harmful cells. Excessive apoptosis has however been linked to a number of diseases including proteinuric kidney disease and DKD, and is believed to enhance the disease progression. READ MORE

4. 2. Regulation of apoptosis and steroidogenesis in ovarian preovulatory granulosa cells

   Author : Eva Svensson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; apoptosis; granulosa cells; luteinizing hormone; progesterone receptor; RU 486; Org 31710; leptin; steroidogenesis;

   Abstract : Only a minute fraction of ovarian follicles present in a foetal ovary will complete the path to ovulation. The majority of the follicles will instead undergo atresia, a hormonally controlled apoptotic process. Apoptosis occurs throughout follicle development, with an extensive reduction in the number of follicles present at birth. READ MORE

5. 3. Targeting apoptosis-inducing factor as a novel therapeutic strategy for preventing perinatal brain injury

   Author : Juan Rodriguez; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AIF; neonatal; mouse; hypoxia-ischemia; AIF CypA complex; apoptosis; asphyxia; CHCHD4;

   Abstract : Perinatal complications such as asphyxia can cause brain injuries that are often associated with subsequent neurological deficits. The mechanisms of perinatal brain injury are not fully understood, but mitochondria play a prominent role, not only due to their central function in metabolism, but also because many proteins with apoptosisrelated functions are located in the mitochondrion. READ MORE

6. 4. Monitoring of extracellular substances after spontaneous and experimental subarachnoid hemorrhage

   Author : Magnus Runnerstam; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Subarachnoid hemorrhage; Microdialysis; Amino acids; GFAP; Iron; Apoptosis;

   Abstract : Even though survival is considerably enhanced after surgical treatment of an aneurysmal subarachnoid hemorrhage (SAH), there is a critical period, which keeps the patient in intensive care for days or even weeks. Complications, such as vasospasm, ischemia and brain edema ultimately lead to further brain damage. READ MORE

7. 5. Voltage-dependent anion channels (VDAC) in the plasma membrane induce apoptosis

   Author : Nesar Akanda; Fredrik Elinder; Tuula Jalonen; Linköpings universitet; []
   Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Physiology; Apoptosis; Cell membrane; Hippocampus; Membrane potentials; Neurons; Voltage-dependent anion channels; Medicine; Medicin;

   Abstract : Apoptosis, or programmed cell death, is essential for proper development and functioning of the body systems. During development, apoptosis plays a central role to sculpt the embryo, and in adults, to maintain tissue homeostasis by eliminating redundant, damaged or effete cells. Therefore, a tight regulation of this process is essential. READ MORE