Search for dissertations about: "Apotosis"

Found 3 swedish dissertations containing the word Apotosis.

  2. 1. Innervation patterns and locally produced signal substances in the human patellar tendon : of importance when understanding the processes of tendinosis

    Author : Patrik Danielson; Sture Forsgren; Håkan Alfredson; Graham Riley; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; patellar tendon; innervation; tendinosis; tendinopathy; acetylcholine; catecholamines; muscarinic receptors; adrenergic receptors; Anatomy; Anatomi;

    Abstract : Tendinosis is a condition of chronic pain that afflicts several human tendons, not least the patellar tendon, in which case it is often clinically referred to as ‘jumper’s knee’. The exact mechanisms behind tendinosis are yet not fully understood. READ MORE

  4. 2. Alterations in activity and specificity of intracellular proteolysis in disease pathogenesis

    Author : Lei Lu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Proteasome; Ubiquitin; Cancer; Neuro-degeneration; Poly-Glutamine; Apoptosis; Tripeptidyl-Peptidase II; Stress; IAP;

    Abstract : The ubiquitin-proteasome pathway (UPP) plays a fundamental role in many basic cellular processes. Virtually all events in cellular physiology include control by the ubiquitin-proteasome pathway. Ubiquitinated substrates are degraded by the 26S proteasome, a large multicatalytic protease complex. READ MORE

  5. 3. Development of intimal hyperplasia in transplant arteriosclerosis

    Author : Piotr Religa; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Vascular disease is the main cause of disability and mortality in the western world and the major limiting factor for long- term survival of transplanted organs. Occlusive vascular lesions lead to ischemia and structural changes in organs and in transplant arteriosclerosis and restenosis after endovascular procedures, narrowing of the vessel lumen is partly due to intimal hyperplasia caused by smooth muscle cells (SMCs). READ MORE