Search for dissertations about: "Arne Egesten"

Found 5 swedish dissertations containing the words Arne Egesten.

  2. 1. The mast cell transcriptome and the evolution of granule proteins and Fc receptors

    Author : Srinivas Akula; Lars Hellman; Sandra Kleinau; Arne Egesten; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mast cell; Fc receptors; Granule serine protease; Evolution and transcriptome.; Immunologi; Immunology;

    Abstract : Protection against disease-causing pathogens, known as immunity, involves numerous cells organs, tissues and their products. To able to understand the biology of immune cells (hematopoietic cells) and their role in an immune system, we have used several different methods, including transcriptome analyses, bioinformatics, production of recombinant proteins and analyses of some of them, focusing on the granule proteases by substrate phage display. READ MORE

  4. 2. Mast cells and their progenitors in respiratory diseases : Understanding their connection to lung function and airway inflammation

    Author : P. Abigail Alvarado-Vazquez; Jenny Hallgren; Arne Egesten; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cells; mast cell progenitors; pulmonary function test; allergic airway inflammation; experimental asthma model; Immunologi; Immunology;

    Abstract : Mast cells are rare immune cells involved in allergic diseases, including asthma. These cells are derived from mast cell progenitors (MCps) that migrate to the peripheral tissues via the blood in response to allergic or non-allergic stimuli. READ MORE

  5. 3. Fatigue and Peripheral Muscle Dysfunction: Studies on Vitamin D Status, Muscle Metabolism and Systemic Inflammation in Patients with COPD : Aspects of COPD severity beyond FEV1 and exacerbations

    Author : Magnus Kentson; Lennart Persson; Jan-Erik Karlsson; Fredrik Nyström; Arne Egesten; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : BackgroundThe severity of Chronic Obstructive Pulmonary Disease (COPD) is usually described in terms of forced expiratory volume in one second (FEV1) and number of exacerbations. However, COPD is a complex disease with different ways of expression, involving pulmonary symptoms, extra pulmonal manifestations and comorbidities, which altogether affect the patient by contributing to reduced functional capacity, increased shortness of breath, reduced health-related quality of life and increased mortality. READ MORE

  6. 4. Proteolytic imbalance in COPD : epidemiological and clinical aspects

    Author : Robert Linder; Anders Blomberg; Anne Lindberg; Annelie F. Behndig; Arne Egesten; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Matrix metalloproteinases; MMP-9; MMP-12; lung function decline; epidemiology; COPD; OLIN; KOLIN; medicin; Medicine;

    Abstract : Background: The complete pathologic mechanism behind the development of chronic obstructive pulmonary disease (COPD) remains unclear, but several risk factors have been identified, of which smoking is the most common. Proteolytic imbalance contributes to lung tissue degradation and is related to both smoking and COPD symptoms. READ MORE

  7. 5. The role of anti-collagen type II antibodies in the pathogenesis and prognosis of rheumatoid arthritis

    Author : Vivek Anand Manivel; Johan Rönnelid; Arne Egesten; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; Anti-collagen type II antibodies; HLADRB1*; Granulocytes; prognosis; ;

    Abstract : Rheumatoid arthritis (RA) which affects 0.5-1% of the world population and is characterised by joint erosions and presence of the autoantibodies anti-citrullinated protein antibodies (ACPA) and rheumatoid factor. READ MORE