Search for dissertations about: "Articular: metabolism"
Showing result 1 - 5 of 18 swedish dissertations containing the words Articular: metabolism.
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1. Metabolism of articular cartilage proteoglycans in vitro : effects of synovial membrane products and mechanical pressure
Abstract : The effect of synovial membrane products and mechanical pressure upon the metabolism of articular cartilage proteoglycans has been studied in vitro. The degradation of cartilage proteoglycans was studied in an organ culture system and measured as the release of [35S ] sulphate from prelabelled cartilage. READ MORE
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2. Intra-articular Glucocorticoid Treatment : Efficacy and Side Effects
Abstract : Intra-articular glucocorticoid injection therapy is frequently used to relieve symptoms of arthritis, but there is considerable variation in injection routines among physicians. One issue of debate concerns the importance of synovial fluid aspiration during the injection procedure. READ MORE
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3. Articular cartilage proteoglycan biosynthesis and sulfation
Abstract : Glucosamine (GlcN) and glucosamine sulfate (GS) have been used to treat the patients with osteoarthritis(OA) as a disease-modifying agent. Previousin vitro studies have focused on the effects of GlcN or GSon cartilage metabolism, whereas in vivo studies have investigated their potential for the treatment of OA. READ MORE
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4. Chondrocyte-matrix interactions: with emphasis on the collagen binding integrin a10ß1
Abstract : The work in this thesis has been focused on chondrocyte integrins and their interaction with the matrix proteins chondroadherin (CHAD) and collagen type II (CII). Affinity purification of CHAD-binding proteins from chondrocyte lysate, followed by immunoprecipitation of EDTA-eluted material identified alpha2beta1 as a CHAD-binding integrin. READ MORE
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5. Influences of in vivo and in vitro loading on the proteoglycan synthesis of articular cartilage chondrocytes
Abstract : In this study, the biosynthesis of proteoglycans (PGs) was examined in articular cartilage of canine hip joint after long-distance running experiment and in bovine chondrocyte cultures during in vitro loading with hydrostatic pressure. In addition, new assays were developed for more sensitive quantitation of glycosaminoglycans (GAGs) and PGs. READ MORE