Search for dissertations about: "Artificial in recruitment"

Showing result 6 - 10 of 18 swedish dissertations containing the words Artificial in recruitment.

  2. 6. The role of the lymph node stroma in cancer and aging

    Author : Tove Bekkhus; Maria H. Ulvmar; Timothy P. Padera; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lymph node; Stroma; High endothelial venule HEV ; Lymphatic endothelial cells LECs ; Breast cancer; Metastasis; Lipomatosis; Medicinsk vetenskap; Medical Science;

    Abstract : The function of the lymph node (LN) stroma is crucial for the induction of an adaptive immune response. The stroma includes lymphatic vessels, high endothelial venules (HEVs) and mesenchymal cells (MCs). In this thesis, I have been investigating the role of the LN stroma in cancer and aging. READ MORE

  4. 7. Functions of integrin receptors in extravascular neutrophil migration and respiratory burst

    Author : Joachim Werr; Karolinska Institutet; Karolinska Institutet; []
    Keywords : adhesion molecules; leukocyte migration; neutrophils; chemotaxis; integrins; respiratory burst; leukocyte extravasation; extracellular matrix; intravital microscopy; acute inflammation;

    Abstract : Leukocytes circulate in the vasculature, but, must leave the blood stream and migrate through the surrounding tissue to exert their protective functions in inflammation. Numerous studies have revealed that intravascular leukocyte-endothelial cell interactions involve functions of adhesion molecules belonging to the selectin and integrin receptor families. READ MORE

  5. 8. Peptide nucleic acid conjugates as artificial ribonucleases : Cu2+ and Zn2+-dependent PNAzymes

    Author : Olivia Luige; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Synthetic modified oligonucleotides are gaining momentum as powerful therapeutic tools used in the treatment of life-threatening diseases. Degradation of disease-related RNA sequences is one of the goals achieved with oligonucleotide therapeutics, albeit the currently available technologies rely on the recruitment of endogenous enzymes, RNase H or RISC, limiting the chemical architecture of oligonucleotide drugs. READ MORE

  6. 9. Habitat requirements and preservation of the beetle assemblages associated with hollow oaks

    Author : Nicklas Jansson; Per Milberg; Karl-Olof Bergman; Simon Grove; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : One of the most endangered assemblages of species in Europe is saproxylic beetles associated with old trees. To be able to conserve these species there is a need of developing methods to survey the fauna and to evaluate the conservation value of different oak habitats, develop instruments for landscape planning and detailed knowledge of species habitat requirements. READ MORE

  7. 10. RP59 : a novel stem cell protein and mapping of its expression

    Author : Anders Krüger-Almerén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The purpose of this thesis was to study the expression pattern of a novel protein daring developmental processes. Firstly we identified so far unknown mRNA sequences coding for frequently expressed proteins in primitive mesenchymal cells in bone marrow and osteoblasts. READ MORE