Search for dissertations about: "Artita Srimanee"
Found 2 swedish dissertations containing the words Artita Srimanee.
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1. Peptide-based delivery to glioblastoma cells studied by the blood-brain barrier model
Abstract : Crossing the blood-brain barrier (BBB) is a great challenge for delivery of highly charged macromolecules such as nucleic acids and proteins to the brain. Cell-penetrating peptides (CPPs) are promising vectors to deliver various cargoes ranging from small molecules to large molecules such as antibodies, proteins, and nucleic acids. READ MORE
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2. Cell-penetrating peptides targeting glioblastomas for nucleic acid delivery in the blood-brain barrier model
Abstract : Glioblastoma multiforme is the most aggressive form of malignant brain tumor with poor prognosis. The efficacy of brain cancer treatment by chemotherapeutics is limited by the blood-brain barrier (BBB) which allows less than 2% of the small molecules and blocks almost all the macromolecules to transport into the brain. READ MORE