Search for dissertations about: "Arunkumar"

Found 2 swedish dissertations containing the word Arunkumar.

  1. 1. Evolution of the G protein-coupled receptor signaling system : Genomic and phylogenetic analyses

    Author : Arunkumar Krishnan; Helgi Schiöth; Torgeir Hvidsten; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; GPCRs; G proteins; Sensory system; Signal transduction; Olfaction; Chemosensation; Hemichordates; Sponges; Porifera; Bilaterians; Holozoans; Fungi; Opisthokonts; Bioinformatics; Bioinformatik;

    Abstract : Signal transduction pathways mediated by G protein-coupled receptors (GPCRs) and their intracellular coupling partners, the heterotrimeric G proteins, are crucial for several physiological functions in eukaryotes, including humans. This thesis describes a broad genomic survey and extensive comparative phylogenetic analysis of GPCR and G protein families from a wide selection of eukaryotes. READ MORE

  2. 2. Viperin, a multifunctional radical SAM enzyme : biogenesis and antiviral mechanisms

    Author : Arunkumar Upadhyay; Anna K. Överby; Niklas Arnberg; Richard Lundmark; Michael Beard; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Viperin (virus-inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) is an interferon-induced antiviral protein. It has three distinct functional domains: the N-terminal domain, the radical SAM (S-adenosylmethionine) domain for binding iron-sulphur cluster, and the C-terminus domain. READ MORE