Search for dissertations about: "As V"
Showing result 11 - 15 of 4542 swedish dissertations containing the words As V.
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11. Let's work it out : aspects of the occupational situation of survivors of allogeneic haematopoietic stem cell transplantation
Abstract : Background: Work is an important part of life and contributes to an individual’s physical and mental well-being. Being diagnosed with a life-threatening haematological disease that requires an allogeneic haematopoietic stem cell transplantation (allo-HSCT) disrupts patients’ occupational situation as most end up on long-term sick leave. READ MORE
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12. Revisiting the urban block in the light of climate change : A case study of Budapest
Abstract : Since the beginning of the twentieth century, the urban block configuration of free-standing buildings has been deemed superior to other built forms, as it provided the necessities of modern healthy living: sunlight and fresh air. In light of climate change, the dissertation aims to reevaluate these long held beliefs and to reintroduce microclimate as an urban design consideration. READ MORE
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13. Epigenic regulation and posttranslational modification of human cytochrome P450s : focus on CYP2W1, CYP1A2 and CYP2C18
Abstract : The cytochrome P450 superfamily represents a very important group of enzymes that are responsible for the metabolism of drugs as well as of endogenous compounds. Many P450s are genetically polymorphic causing important interindividual variability in P450 expression and activity whereas in some cases the basis for interindividual variation has still not been resolved. READ MORE
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14. Caspase activation in human neuroblastoma cells: mechanisms and spatiotemporal aspects
Abstract : Apoptosis is one of the modes of programmed cell death, in which several members of the caspase family of proteases play the central role. However, activation of apoptotic caspases does not necessarily lead to cell death. READ MORE
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15. Unraveling the role of NOTCH3 dysfunction in disease and for therapy development : a focus on CADASIL
Abstract : The Notch signaling pathway, including the Notch3 receptor, is involved in many pivotal contexts of cell signaling and cell fate determination processes during development and in adulthood. Different mutations in the NOTCH3 receptor, which is highly expressed in vascular smooth muscle cells (VSMC), are associated with various diseases, including developmental disorders, several forms of cancer, and vascular dementia. READ MORE