Search for dissertations about: "Asparaginase"
Found 3 swedish dissertations containing the word Asparaginase.
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1. Mechanisms of cancer cell death by mutant p53-reactivating compound APR-246
Abstract : Tumor suppressor TP53 is the most frequently mutated gene in cancer. A majority of TP53 mutations result in a mutant p53 that disrupts its DNA binding capabilities but may also acquire novel gain-of-function activities that contribute to tumor growth. READ MORE
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2. Factors affecting growth, differentiation and apoptosis of osteoblastic and osteosarcoma cells
Abstract : Osteoblasts play a fundamental role in determining bone structure and function. These cells originate from mesenchymal stem cells (MSCs) and through proliferation and differentiation develop into preosteoblasts and then into mature cells. READ MORE
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3. Impact of body mass index on outcome, toxicity and pharmacokinetics in patients with acute lymphoblastic leukemia
Abstract : Background: Overweight and obesity are growing health problems. Obesity has been associated with both a higher risk of contracting cancer and increased cancer-related mortality in adults. The impact in children with cancer, and more specifically with acute lymphoblastic leukemia (ALL), is less explored. READ MORE