Search for dissertations about: "Asthma: immunology"

Showing result 1 - 5 of 21 swedish dissertations containing the words Asthma: immunology.

  1. 1. Induction of Mast Cell Apoptosis via Granule Permeabilization : A Novel Approach to Target Mast Cells

    Author : Aida Paivandy; Gunnar Pejler; Magda Babina; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Granules; Apoptosis; Reactive oxygen species; ROS; Lysosomotropic agents; Mefloquine; Immunologi; Immunology; Biokemi; Biochemistry;

    Abstract : Mast cells are densely granulated tissue-resident immune cells that play an important role in orchestrating inflammatory responses. Dysregulated increases in the numbers and activation status of mast cells can have deleterious consequences for the body in various inflammatory diseases. READ MORE

  2. 2. Mast Cell Progenitor Trafficking in Allergic Airway Inflammation

    Author : Joakim Dahlin; Jenny Hallgren; Hans-Reimer Rodewald; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Mast cells; mast cell progenitors; allergy; asthma; allergic airway inflammation; IgE; lung; CD11c;

    Abstract : Mast cell progenitors originate from the bone marrow and migrate to the lungs via the blood. During maturation, these cells acquire granules that contain a potent array of bronchoconstrictive mediators. READ MORE

  3. 3. Purification, characterization and immunological studies of rat urinary proteins causing allergy in humans

    Author : Cecilia Bayard; Gabriel Peltre; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; allergen; laboratory animal allergy; rat urinary protein; Rat n 1.02; a2u-globulin; purification; chemiluminescence; immunologi; Immunology;

    Abstract : Rats are among the most frequently used laboratory animals and allergy to them constitutes a common occupational problem. Approximately 20-30% of the persons engaged in work with laboratory animals acquire symptoms of allergy. READ MORE

  4. 4. New Aspects of Mast Cell Progenitors in Health and Disease

    Author : Maya Salomonsson; Jenny Hallgren Martinsson; Silvia Bulfone-Paus; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Mast cell progenitor; Lung function; Bone marrow; Blood; Activation; Chemotactic receptors;

    Abstract : Mast cells are tissue-resident immune cells that are well known for their involvement in asthma and allergy. They originate in the fetal yolk sac, or in the bone marrow. From the bone marrow, they are released as immature progenitors that are transported via the blood circulation to the peripheral tissue, where they mature. READ MORE

  5. 5. Mechanisms triggering the recruitment of mast cell progenitors to the lung and regulation of mast cell degranulation

    Author : Behdad Zarnegar; Jenny Hallgren; Madeleine Rådinger; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Mast cell progenitors; Recruitment; Lung; Virus; Influenza; Innate immunity; Poly I:C; IL-33; VAAT; SLC10A4; Degranulation;

    Abstract : Mast cells stem from the bone marrow and migrate via the blood as mast cell progenitors. Upon arrival in peripheral tissues, they develop into mast cells. These rare immune cells have numerous granules that contain large amounts of pro-inflammatory mediators. READ MORE