Search for dissertations about: "Astrid Gräslund"

Showing result 1 - 5 of 24 swedish dissertations containing the words Astrid Gräslund.

  1. 1. Radiation-induced free radicals in DNA studied by electron paramagnetic resonance

    Author : Astrid Gräslund; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  2. 2. Modulation of Alzheimer's amyloid β peptide self-assembly : Insights into molecular mechanisms of peptide aggregation associated with Alzheimer's disease

    Author : Axel Abelein; Astrid Gräslund; Adriaan Bax; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Biophysics; biofysik;

    Abstract : Misfolding of proteins and peptides is closely linked to several neurodegenerative disorders, among them Alzheimer's disease (AD), the most prominent example of brain diseases. The self-assembly of the amyloid β peptide (Aβ) into amyloid fibrils is one histologic hallmark of AD. READ MORE

  3. 3. Modulation of amyloid β peptide self-assembly : Aggregation mechanisms associated with Alzheimer's disease

    Author : Axel Abelein; Astrid Gräslund; Magnus Wolf-Watz; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Biophysics; biofysik;

    Abstract : .... READ MORE

  4. 4. Biophysical studies of cell-penetrating peptides and of the RNR inhibitor Sml1

    Author : Elsa Bárány-Wallje; Astrid Gräslund; Joachim Seelig; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; cell-penetrating peptides; transportan; bicelles; Sml1; Biophysics; Biofysik; Biophysics; biofysik;

    Abstract : Several short peptides, so called cell-penetrating peptides, have the capability to transport large hydrophilic cargos through the cell membrane. The objective is to use these peptides as drug carriers and thereby enhance the uptake of drugs into cells.Three different cell-penetrating peptides are characterized in this thesis. READ MORE

  5. 5. Dynorphin A – Interactions with receptors and the membrane bilayer

    Author : Johannes Björnerås; Lena Mäler; Astrid Gräslund; Göran Widmalm; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Biophysics; biofysik; Biochemistry; biokemi;

    Abstract : The work presented in this thesis concerns the dynorphin neuropeptides, and dynorphin A (DynA) in particular. DynA belongs to the wider class of typical opioid peptides that, together with the opioid receptors, a four-membered family of GPCR membrane proteins, form the opioid system. READ MORE