Search for dissertations about: "Astrid Ottosson-Seeberger"

Found 1 swedish dissertation containing the words Astrid Ottosson-Seeberger.

2. 1. Cardiovascular and metabolic effects of endothelins in man : an experimental and clinical study

   Author : Astrid Ottosson-Seeberger; Karolinska Institutet; Karolinska Institutet; []
   Keywords : endothelin-1; big ET-1; C-terminal big ET-1 22-3 8 fragment; hemodynamic; blood flow; fractional extraction; conversion; plasma half-life; end-stage renal failure; ischemic heart disease; hemodialysis; high-flux membrane; glucose uptake; insulin sensitivity;

   Abstract : Increased plasma concentrations of endothelin-1 (ET-1) and of its propeptide big endothelin-1 have been reported in diseases associated with endothelial dysfunction, cardiovascular remodelling and insulin resistance. In this thesis, we studied the hemodynamic effects of big ET-1 in healthy humans focusing on the mechanisms of the effects (study I-IV). READ MORE