Search for dissertations about: "Astrocytoma"

Showing result 21 - 24 of 24 swedish dissertations containing the word Astrocytoma.

  1. 21. Alterations of cell cycle control genes in human astrocytomas

    Author : Esther E Schmidt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cytogenetic analyses and molecular genetic studies have revealed a number of chromosomal regions deleted or amplified in astrocytic tumors, presumably harboring tumor suppressor genes and oncogenes involved in astrocytic oncogenesis. Astrocytomas represent the most common subgroup of primary intracranial tumors. READ MORE

  2. 22. Neurotoxicity of methylmercury : analysis of molecular mechanisms and behavioral alterations

    Author : Elisabetta Daré; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Apoptosis; oxidative stress; neurons; glia; rats; dopamine; locomotion; learning and memory; environmental pollutants;

    Abstract : MethyImercury (MeHg) is a global pollutant that is toxic for the nervous system, especially during development. Contaminated fish is the main route of human exposure. Recent studies have indicated that neurological alterations in humans may occur even after exposure to fairly low levels of MeHg. READ MORE

  3. 23. p16INK4A and p15INK4B in senescence, immortalization and cancer : gene transfer by adenovirus vectors

    Author : Jonas Fuxe; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The astrocytic gliomas are the most common form of brain tumors in humans. The malignant progression from low grade (astrocytoma, grade II) to high-grade (glioblastoma multiforme, grade, IV) astrocytomas is well documented and is accompanied by an increasing number of genetic aberrations. READ MORE

  4. 24. Cell cycle regulatory genes in human astrocytic tumors

    Author : Koichi Ichimura; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cancer is a genetic disorder of somatic cells. Neoplastic transformation and malignant progression may be a consequence of accumulated multiple genetic changes in a cell. Astrocytic gliomas are the commonest brain tumors in humans. READ MORE