Search for dissertations about: "Atovaquone"

Showing result 1 - 5 of 7 swedish dissertations containing the word Atovaquone.

  1. 1. Development of Field-adapted Analytical Methods for the Determination of New Antimalarial Drugs in Biological Fluids

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Niklas Lindegårdh; Uppsala universitet.; Högskolan Dalarna.; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi; Analytical Chemistry; analytisk kemi; Analytical chemistry; LC; liquid chromatography; biological samples; SPE; solid phase extraction; validation; antimalarial drugs; amodiaquine; piperaquine; atovaquone; dried blood spots; Analytisk kemi;

    Abstract : This thesis deals with the development of analytical methods for the determination of new antimalarial drugs in biological fluids. The goal was to develop methods that facilitate clinical studies performed in the field, such as capillary blood sampling onto sampling paper. READ MORE

  2. 2. Pharmacokinetics and dynamics of atovaquone and proguanil (Malarone R)

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Mita M Thapar; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malarone; Atovaquone; proguanil; cycloguanil; pharmacokinetics; drug interactions; pharmacodynamics; resistance;

    Abstract : Malarone® is a fixed dose combination of atovaquone and proguanil and is mainly used for prophylaxis against P. falciparum malaria as an alternative to Lariamo® or chloroquine+proguanil. READ MORE

  3. 3. Development of Analytical Methods for the Determination of Antimalarials in Biological Fluids

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Daniel Blessborn; Uppsala universitet.; Högskolan Dalarna.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi; Malaria; Chloroquine; Quinine; Sulfadoxine; Pyrimethamine; Mefloquine; Lumefantrine; Amodiaquine; Pyronaridine; Proguanil; Atovaquone; Sampling paper; Dried blood spots; Capillary blood; Antimalarial drugs; Solid-phase extraction; Liquid chromatography.;

    Abstract : The aim of this thesis was to develop analytical methods for measuring antimalarial drugs in biological fluids. Solid phase extraction (SPE) was used for the enrichment and purification of the drugs. READ MORE

  4. 4. Development of Analytical Methods for Measurement of Drugs against Malaria in Plasma and Whole Blood

    University dissertation from Uppsala : Department of Physical and Analytical Chemistry, Analytical Chemistry, Uppsala University

    Author : Daniel Blessborn; Uppsala universitet.; Högskolan Dalarna.; [2006]
    Keywords : Malaria Method Development Pyronaridine Atovaquone Proguanil Malarone Amodiaquine;

    Abstract : The aim of this thesis was to develop analytical methods for measuring drugs in blood and/or plasma. Solid phase extraction was used for the enrichment and purification of the drugs from the sample matrix. READ MORE

  5. 5. Experimental Pharmacodynamic and Kinetic Studies Related to New Combination Therapies against Falciparum Malaria

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Seema Gupta; Karolinska Institutet.; Karolinska Institutet.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Artemisinin (ART) class of compounds are of special interest due to their rapid onset of action and high activity against multidrug resistant malaria. The major drawback in monotherapy with ART and its derivatives is the high rate of recrudescent infection. READ MORE