Search for dissertations about: "Autoantibody"

Showing result 1 - 5 of 117 swedish dissertations containing the word Autoantibody.

  2. 1. Autoantibody profiling in autoimmune diseases

    Author : Shaghayegh Bayati; Peter Nilsson; Elisa Pin; Peter Heeringa; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmunity; Autoantibodies; Vasculitis; Systemic Sclerosis; affinity proteomics; Biotechnology; Bioteknologi;

    Abstract : Autoimmune disease diagnosis and definition of prognosis can be challenging. Patients with the same autoimmune disease could present with very heterogeneous symptoms. Therefore, there is a need to understand the disease better to improve patients’ diagnosis, and classification, and tailor the treatment. READ MORE

  4. 2. Gestational Diabetes Mellitus- Future risk for mother and child

    Author : Charlotta Nilsson; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gestational Diabetes Mellitus; autoantibody; GADA; ZnT8A; C-peptide; overweight; offspring;

    Abstract : Gestational diabetes mellitus (GDM) occurs as a complication in 2% of all pregnancies in Sweden. Women with GDM have a substantial risk of developing type 2 diabetes later in life, but the risk of developing type 1 diabetes is also increased. GDM increases the risk for macrosomia and caesarean delivery. READ MORE

  5. 3. On the application and validation of multiplexed affinity assays

    Author : Tea Dodig-Crnković; Jochen M. Schwenk; Mun-Gwan Hong; Peter Nilsson; Norman Leigh Anderson; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Affinity proteomics; Antibody; Autoantibody; Multiplexed assays; Protein microarray; Plasma proteins; Suspension bead array; Bioteknologi; Biotechnology;

    Abstract : Proteins are essential macromolecules that carry out complex functions in human cells, tissues, and organs. They regulate a diverse set of biological processes and protect against pathogens. However, dysregulation or malformation of proteins can cause disease. READ MORE

  6. 4. Purine synthesis inhibition in experimental lupus

    Author : Charlotte A Jonsson; Göteborgs universitet; []
    Keywords : SLE; Mycophenolate mofetil; MRLlpr lpr mice; cytokine; autoantibody;

    Abstract : Systemic lupus erythematosus (SLE) is an autoimmune disease that mainly affects women. The effect of the immune modulating drug mycophenolate mofetil (MMF) on experimental SLE was investigated. READ MORE

  7. 5. Liver Transplantation-associated Food Allergy and Eosinophilic Gastrointestinal Inflammation in Children - Clinical and Immunological Aspects

    Author : Timo Käppi; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; liver transplantation; food allergy; autoantibody; immune dysregulation; collagenous gastritis; eosinophilic esophagitis; eosinophilic inflammation; eosinophil; children;

    Abstract : This thesis focuses on three recently described childhood-onset gastrointestinal disorders: liver transplantation-associated food allergy (LTFA), collagenous gastritis (CG) and eosinophilic esophagitis (EoE). Its aim was to gain additional understanding of both the clinical disease characteristics and the associated immunological aberrations in these conditions. READ MORE