Search for dissertations about: "Autotransport"

Found 5 swedish dissertations containing the word Autotransport.

  1. 1. Influence of recombinant passenger properties and process conditions on surface expression using the AIDA-I autotransporter

    Author : Martin Gustavsson; Gen Larsson; Peter Neubauer; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; AIDA-I; Autotransport; Biocatalysis; Escherichia coli; Live vaccines; Surface expression;

    Abstract : Surface expression has attracted much recent interest, and it has been suggested for a variety of applications. Two such applications are whole-cell biocatalysis and the creation of live vaccines. READ MORE

  2. 2. Improved detection and performance of surface expression from the AIDA-I autotransporter

    Author : Johan Jarmander; Gen Larsson; Ulrika Rova; Ines Ezcurra; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; surface expression; autotransport; AIDA-I; Escherichia coli; proteolysis; detection tag;

    Abstract : Surface expression of recombinant proteins has attracted a lot of attention due to its potential in applications such as enzyme production, vaccine delivery and bioremediation. Autotransporters have been used for surface expression of a variety of proteins, but the expression systems reported in literature have typically been inflexible and incapable of detecting proteolysis, thereby limiting surface expression yield. READ MORE

  3. 3. Strategies for improved Escherichia coli bioprocessing performance

    Author : Johan Jarmander; Gen Larsson; Thomas Egli; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; E. coli; Salmonella; surface expression; autotransport; AIDA-I; lignocellulose; glucose; xylose; arabinose; simultaneous uptake; 3HB; Bioteknologi; Biotechnology;

    Abstract : Escherichia coli has a proven track record for successful production of anything from small molecules like organic acids to large therapeutic proteins, and has thus important applications in both R&D and commercial production. The versatility of this organism in combination with the accumulated knowledge of its genome, metabolism and physiology, has allowed for development of specialty strains capable of performing very specific tasks, opening up opportunities within new areas. READ MORE

  4. 4. Engineering and applications of surface displayed tyrosinase on Escherichia coli

    Author : David Hörnström; Antonius J. A. van Maris; Joachim José; KTH; []
    Keywords : Bioteknologi; Biotechnology;

    Abstract : The rise of biotechnology has provided a toolbox to deal with major challenges related to pollution and health. Microbial enzymes constitute powerful macromolecules with applications in environmental technology, and industrial and medical production. READ MORE

  5. 5. Identification and Characterization of the Moraxella catarrhalis IgD-binding Protein MID

    Author : Andrea Möllenkvist; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; receptor; structure; phase variation; MID; IgD; Moraxella catarrhalis; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Moraxella catarrhalis is now an established human pathogen that frequently colonizes the upper respiratory tract causing most importantly otitis media in children. It has also been associated with sinusitis, laryngitis and lower respiratory tract infections in adults with predisposing conditions such as chronic obstructive pulmonary disease (COPD). READ MORE