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Found 2 swedish dissertations matching the above criteria.

  1. 1. Transcriptional regulation by the thyroid hormone receptor and its viral counterpart : the P75gag-V-erbA oncoprotein

    Author : Gunilla Wahlström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Transcriptional regulation; thyroid hormone; TR; P75gag-v-erbA; repression; Avian erythroblastosis virus; response elements; RXR; retinoids.;

    Abstract : Thyroid hormone binds to specific DNA binding receptors (TRs) in the cell nucleus and thus regulates transcription during development and in some pathological disorders. The gene of the viral TR homologue, v-erbA, is one of two oncogenes encoded in the genome of avian erythroblastosis virus (AEV). READ MORE

  2. 2. The regulatory role of microRNA in human adipocytes and their link to insulin resistance

    Author : Yasmina Belarbi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : White adipose tissue (WAT) is a highly plastic organ which secretes a large number of peptide factors termed adipokines. Increased caloric intake increases WAT mass which results in marked alterations in the secretory pattern. This may be mediated via both transcriptional and post-transcriptional mechanisms. READ MORE