Search for dissertations about: "Axel Rydevik"

Found 1 swedish dissertation containing the words Axel Rydevik.

  1. 1. Drug Metabolites Formed by Cunninghamella Fungi : Mass Spectrometric Characterization and Production for use in Doping Control

    Author : Axel Rydevik; Mikael Hedeland; Ulf Bondesson; David Cowan; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cunninghamella blakesleeana; Cunninghamella elegans; Doping Control; Drug Metabolites; Glucuronide Production; Mass Spectrometry; Reactive Metabolites; Reference Material; Structural Characterization; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Abstract : This thesis describes the in vitro production of drug metabolites using fungi of the Cunninghamella species. The metabolites were characterized with mainly liquid chromatography-mass spectrometry using ion-trap and quadrupole-time-of-flight instruments. A fungal in vitro model has several advantages e.g. READ MORE