Search for dissertations about: "B A Lie"

Showing result 1 - 5 of 29 swedish dissertations containing the words B A Lie.

  1. 1. Cholinesterase inhibitors in Alzheimer's disease : an experimental study on mechanisms of interatcion with muscarinic and nicotinic receptors and neuroprotection

    Author : Anne-Lie Svensson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alzheimer s disease Cholinesterase inhibitors Muscarinic receptors Nicotinic receptors Acetylcholine release Neuroprotection B-amyloid apolipoprotein E;

    Abstract : The overall aim of this thesis was to investigate the mechanisms beyond the interaction of cholinesterase inhibitors (ChEIs) with the cholinergic system in brain, with emphasis on their regulatory and mechanistic effects on subtypes of muscarinic and nicotinic receptors and neuroprotective properties. To investigate muscarinic receptor subtypes in frontal cortices of AD brains, the muscarinic antagonists pirenzepine, AF-DX 116, HHSiD, p-F-HHSiD and himbacine were used in receptor binding assays. READ MORE

  2. 2. Reverse genetic studies of Enterovirus replication

    Author : Anna Sävneby; A. Michael Lindberg; Björn Andersson; Peter Gierow; Jonas Waldenström; Martin Ryan; Linnéuniversitetet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Enterovirus; picornavirus; coxsackievirus; echovirus; rhinovirus; reverse genetics; replication; translation; transfection; cassette vector.; Virology; Virologi;

    Abstract : Enteroviruses belong to the Picornaviridae family and are small icosahedral viruses with RNA genomes of positive polarity, containing a single open reading frame. They mostly cause mild or asymptomatic infections, but also a wide array of diseases including: poliomyelitis, encephalitis, gastroenteritis, aseptic meningitis, myocarditis, hand-foot-and-mouth disease, hepatitis and respiratory diseases, ranging from severe infections to the common cold. READ MORE

  3. 3. The hepatitis B virus – Insights into genetic variability, evolution and Bayesian phylogeographic inference

    Author : Mikael Ingman; Malmö Klinisk virologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatit B; evolutionsbiologi; fylogeni; Hepatitis B; evolutionary dynamics; Phylogeography;

    Abstract : In terms of genome size, the hepatitis B virus is the smallest virus known to infect humans and its compactness with multiple overlapping reading frames puts restraints on the emergence of mutations. In the papers included in this thesis we aimed to investigate genetic variation within the precore and core promoter region and to describe the origin, spread and diversification of HBV genotype A. READ MORE

  4. 4. Tensor Products of Highest Weight Representations and Skew-Symmetric Matrix Equations A+B+C=0

    Author : Ida Säfström; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Highest weight respresentation; tensor product decomposition; orthogonal algebra; skew-symmetric matrix; Horn’s conjecture; moment map; coadjoint orbit; flag manifold; general linear algebra; infinite dimensional unitary representation; general linear algebra;

    Abstract : The question of characterizing the eigenvalues for the sum of two Hermitian matrices, was solved in 1999, after almost a century of efforts. The saturation conjecture for GL_C(n) was proven by Knutson and Tao, filling in the last gap in Horn’s conjecture. READ MORE

  5. 5. Graded lie algebras in local algebra and rational homotopy

    Author : Rikard Bøgvad; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : This thesis consists of three papers, [A – C]The old conjecture that Poincaré-series of local noetherian rings are rational was disproved by Anick in 1979. Building upon his counter-example, as analyzed by Löfwall-Roos, I construct a Gorenstein ring with transcendental Poincaré-series; by a method of Roos this also gives a manifold whose loopspace has transcendental Poinaré-Betti series. READ MORE