Search for dissertations about: "B Ek"

Showing result 1 - 5 of 11 swedish dissertations containing the words B Ek.

2. 1. Transcriptional analysis of mantle cell lymphoma - a global search for cellular origin and therapeutic targets

   Author : Sara Ek; Institutionen för immunteknologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; oncology; cancerology; Cytologi; onkologi; Cytology; somatic mutation; microarray; tumour; mantle cell lymphoma; B cell;

   Abstract : This thesis is based upon four original papers describing the characterisation of mantle cell lymphoma (MCL) tumours and cell lines in comparison with different populations of normal B cells. Gene expression profiling, which were used in the studies, has during recent years developed as an important tool in characterisation of different types of malignancies. READ MORE

4. 2. Fetal hematopoietic cells in early gestation : aspects in view of fetal transplantation

   Author : Sverker Ek; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Fetal stem cells; fetal liver; fetal hematopoiesis; immunological ontogeny; fetal transplantation; cytokines; CD34 enrichment;

   Abstract : The fetus as a patient is a challenge. There are opportunities for early, sometimes life-saving procedures or there may be advantages in prenatal rather than postnatal intervention. This is the case in fetal hematopoietic cell (FHC) transplantation where conditions caused by a defect in blood cell formation may be life-threatening to the fetus. READ MORE

5. 3. Approaches to accelerate methods for solving systems of equations arising in nonlinear optimization

   Author : David Ek; Anders Forsgren; Jacek Gondzio; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nonlinear optimization; mathematical programming; interior-point methods; approximate solutions to systems of linear equations; method of conjugate gradients; quasi-Newton methods; modified Newton methods; Ickelinjär optimering; matematisk programmering; inre-punktsmetoder; approximativa lösningar till linjära ekvationssystem; konjugerade gradientmetoden; kvasi-Newtonmetoder; modifierade Newtonmetoder.; Optimization and Systems Theory; Optimeringslära och systemteori;

   Abstract : Methods for solving nonlinear optimization problems typically involve solving systems of equations. This thesis concerns approaches for accelerating some of those methods. In our setting, accelerating involves finding a trade-off between the computational cost of an iteration and the quality of the computed search direction. READ MORE

6. 4. Use of Recombinant Allergens for Component-Resolved Diagnostics (CRD) in IgE-Mediated Allergy

   Author : Åsa Marknell DeWitt; Pia Ek; Jonas Lidholm; Ronald van Ree; Uppsala universitet; []
   Keywords : Biomedical laboratory science; recombinant allergen; IgE; component-resolved diagnostics; CRD; tropomyosin; Phl p 11; Phl p 4; Pen a 1; Hev b 5; Biomedicinsk laboratorievetenskap;

   Abstract : Immunoglobulin E (IgE)-mediated allergy occurs when our immune system causes a reaction to otherwise harmless substances (allergens). Allergens are predominantly proteins present in biological materials such as pollens, mites, animal epithelia, moulds and foods. READ MORE

7. 5. Immune reconstitution after childhood leukemia. Aspects on immunizations and effects of Ara-C on the innate immune system

   Author : Torben Ek; Göteborgs universitet; []
   Keywords : acute lymphoblastic leukemia; immune reconstitution; immunization; antibody; avidity; ara-C; fever; cytokines;

   Abstract : Children with acute lymphoblastic leukemia (ALL) can be cured with cytotoxic chemotherapy, but myelosuppression and immunosuppression are major side effects causing morbidity and even mortality from infections. Vaccinations with diphtheria toxoid (DT), tetanus toxoid (TT) and protein conjugated Haemophilus influenzae type B (Hib) capsular polysaccharide were used to investigate the adaptive immune system in a controlled study of 31 children after treatment for ALL. READ MORE