Search for dissertations about: "B cell activation"

Showing result 1 - 5 of 541 swedish dissertations containing the words B cell activation.

2. 1. Signaling determinants in Trojan horse-mediated dissemination of Toxoplasma gondii

   Author : Einar B. Ólafsson; Antonio Barragan; Eva Frickel; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apicomplexa; leukocyte motility; dendritic cell; amoeboid migration; host-parasite interactions; podosome; integrin; ITGB1; ECM; MAT; TIMP; MMP; MAPK; Erk; RTK; HGFR; Ras; calcium; VDCC; VGCC; calmodulin; CaMkII; CD63; FAK; SRC; Pi3k; hypermigration; molekylär biovetenskap; Molecular Bioscience;

   Abstract : Toxoplasma gondii is an obligate intracellular parasite that infects all warm-blooded vertebrates including one third of the global human population. While infection is typically asymptomatic in healthy human hosts, reactivated and acute infection in immunosuppressed or immunecompromised individuals can lead to lethal toxoplasmic encephalitis After ingestion, the parasite crosses the intestinal epithelium and rapidly achieves systemic dissemination, ultimately establishing chronic infection in the brain. READ MORE

4. 2. Functional collaboration between HLH transcription factors in B cell development

   Author : Ramiro Gisler; Stamcellscentrum (SCC); []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; E47; Early B cell Factor EBF ; Clinical genetics; Klinisk genetik; HLH proteins; transcription factors; gene expression; B cell development; transcription regulation;

   Abstract : The cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. READ MORE

5. 3. Defining the role of CD47 and SIRPα in murine B cell homeostasis

   Author : Shrikant S Kolan; Per-Arne Oldenborg; Mikael Karlsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cells; CD47; SIRPα; Follicular B cell; Marginal zone macrophages; immunologi; Immunology;

   Abstract : B cell development is a highly organized process, which commences in the fetal liver during embryogenesis and in the bone marrow (BM) after birth. Surface IgM+ immature B cells emigrate from the BM via the blood stream to the spleen and finally differentiate into conventional mature follicular B (FoB) cells and marginal zone (MZ) B cells. READ MORE

6. 4. Adhesion Dependent Signals : Cell Survival, Receptor Crosstalk and Mechanostimulation

   Author : Anjum Riaz; Staffan Johansson; Bengt Hallberg; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Integrins; Signal transduction; Protein kinase B; Akt; PI3K; Heparanase; ROS; Mechanosignalling; Molekylär cellbiologi; Molecular Cellbiology; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi; Cellforskning; Cell Research;

   Abstract : The integrin family of cell surface receptors is evolutionary conserved and found in all multicellular animals. In humans 8-alpha and 18-beta integrins are non-covalently associated into 24 dimers. Integrins mediate cell-extracellular matrix and cell-cell interactions and participate in cell signalling. READ MORE

7. 5. B lymphocyte adhesion and activation

   Author : Pia Björck; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biologi; Cytologi; Cellbiologi;

   Abstract : .... READ MORE