Search for dissertations about: "B-cell epitopes"

Showing result 1 - 5 of 35 swedish dissertations containing the words B-cell epitopes.

  2. 1. Regulation of B cell responses to modified self

    Author : Emilie Grasset; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The immune system needs to be efficient to protect organisms from invading pathogens. Lymphoid organs such as the spleen and lymph nodes are needed to initiate the response. READ MORE

  4. 2. Specifity and genetic control of B cell reactivity in experimental arthritis

    Author : Patrik Wernhoff; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serologi; transplantation; Genetics; cytogenetics; Genetik; cytogenetik; Immunologi; Autoimmunity B-cell response Epitope Genetics Linkage Analysis; Immunology; serology;

    Abstract : Collagen-induced arthritis (CIA) and pristane-induced arthritis (PIA) are animal models for human rheumatoid arthritis (RA), and can be induced in susceptible mouse and rat strains. CIA is induced by immunization of type II collagen (CII), a cartilage specific protein together with Freund’s adjuvant. READ MORE

  5. 3. B cell responses against the HIV-1 envelope glycoproteins

    Author : Pia Dosenovic; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The fine specificities of vaccine-elicited B cell responses against complex proteins are not well understood, including those directed against the HIV-1 envelope glycoproteins (Env). Env is the only surface-exposed viral protein and hence a major vaccine target, in particular the conserved determinants of Env. READ MORE

  6. 4. The regulation of B cell responses in systemic autoimmunity

    Author : Amanda Duhlin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Our immune system is a complex network made up of physical barriers and specialized proteins, cells and organs that all work together to prevent pathogens from causing disease in the body. Once the immune system has successfully mounted an immune response upon intrusion of a pathogen it will mount an immediate and stronger response against any subsequent exposure to it. READ MORE

  7. 5. Elicitation and enhancement of T and B cell responses

    Author : Hannes Uchtenhagen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The Major histocompatibility complex class I (MHC-I) has been characterized in such great depth that a number of its key properties are well understood and part of its behavior can even be predicted. It is therefore intriguing that the impact of small epitope modifications on immunogenicity and the elicitation of T-cell repertoires remain often unpredictable and full of surprises. READ MORE