Search for dissertations about: "B-cell"

Showing result 1 - 5 of 502 swedish dissertations containing the word B-cell.

  1. 1. Aggressive B-cell Lymphomas Studies of Treatment, FDG-PET Evaluation and Prognostic Factors

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Magdalena Adde; Gunilla Enblad; Hans Hagberg; Anna Laurell; Tor Ekman; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi; Oncology; Onkologi;

    Abstract : To improve outcome in young, high-risk lymphoma patients, treatment was intensified, adding etoposide and rituximab to standard CHOP treatment. Granulocyte-colony stimulating factor (G-CSF) enabled treatment bi-weekly. Results were promising: overall (OS) and event-free survival (EFS) 79% and 60% respectively, median follow up 27 months. READ MORE

  2. 2. Studies on Molecular Genetics of B cell Development

    University dissertation from Panagiotis Tsapogas, Section for Immunology, BMC I-13, S-221 84, Lund

    Author : Panagiotis Tsapogas; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunoglobulin; gene expression; B cell; EBF; class switching; TGF-beta; Immunology; transplantation; serologi; Immunologi; serology;

    Abstract : The development of immature progenitor cells into highly differentiated effector cells is a process central in modern medicine with applications in the fields of cell therapy as well as oncology. This thesis is focused on the molecular mechanisms that control the development of B lymphocytes. READ MORE

  3. 3. Protein kinases and phosphatases in B-cell lymphoma

    University dissertation from Inst för Laboratoriemedicin, Avd för tumörbiologi, Malmö Universitetssjukhus, Lunds Universitet

    Author : Marie Fridberg; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HePTP; PTEN; PKC-beta 2; B-cell; lymphoma; kinases; ZAP70; phosphatase; SHP2;

    Abstract : Around 2000 persons are diagnosed with lymphoma in Sweden each year. There are many subgroups described for this form of cancer and the great majority is derived from B-cells. The most common subgroup is Diffuse large B-cell lymphoma (DLBCL), a highly aggressive disease where only half of the patients are cured. READ MORE

  4. 4. Functional collaboration between HLH transcription factors in B cell development

    University dissertation from Ramiro Gisler, Stem cell laboratory, BMC, B12, Klinikg.26, 22184 Lund, Sweden

    Author : Ramiro Gisler; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; E47; Early B cell Factor EBF ; Clinical genetics; Klinisk genetik; HLH proteins; transcription factors; gene expression; B cell development; transcription regulation;

    Abstract : The cells in B cell development can be divided into several subgroups or fractions, e.g. early-pro-B-, pro-B, large-pre-B-, small-pre-B-, immature and mature B cells, where the stages reflect the maturity degree of the cells. READ MORE

  5. 5. Immunoglobulin Gene Analysis in Different B cell Lymphomas With Focus on Cellular Origin and Antigen Selection

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mia Thorsélius; Richard Rosenquist Brandell; Christer Sundström; Anders Rosén; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; B cell lymphoma; Immunoglobulin; V gene; somatic hypermutation; antigen selection; quantitative PCR; Genetik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik;

    Abstract : B cell lymphoma (BCL) comprises a biologically and clinically heterogeneous group of tumors deriving from different stages of B cell development. The immunoglobulin (Ig) variable heavy chain (VH) gene rearrangement is unique for each BCL and can be used to reveal cellular origin, to study signs of antigen selection and to quantify tumor cell load. READ MORE