Search for dissertations about: "B-myc"

Found 1 swedish dissertation containing the word B-myc.

2. 1. Studies of myc gene expression and a novel endoribonuclease activity

   Author : Anders Wennborg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : c-myc; B-myc; heat-shock; mRNA degradation; endoribonucleases; AUUUAmotifs; RNase E.;

   Abstract : The general aim of this work was to study the regulation of cellular oncogene expression, with emphasis on the c-myc gene, which is de-regulated in several human and animal tumors. The steady-state expression level of c-myc mRNA or protein was analyzed in panels of human Blymphoid cell lines with different growth and transformation properties, and the general observation was a co-variation between high c-myc expression and a more malignant phenotype of the cell lines. READ MORE