Search for dissertations about: "BALB c"

Showing result 1 - 5 of 51 swedish dissertations containing the words BALB c.

2. 1. Murine plasmacytomagenesis : an experimental model of B-cell neoplasia

   Author : Santiago C Silva; Karolinska Institutet; Karolinska Institutet; []
   Keywords : mouse plasmacytomas; chromosomal translocation; chimeric mice; MYC-transgenic mice; ;

   Abstract : A chromosomal translocation which results in the illegitimate activation of the c-myc proto-oncogene by one of the three immunoglobulin (Ig) loci is invariably associated with human Burkitt's Lymphoma (BL), mouse plasmacytoma (MPC) and rat immunocytomas (RIC). In the MPC system a genetic predisposition linked to the BALB/c strain has been suggested. READ MORE

4. 2. Peripheral Regulation of Pain and Itch

   Author : Elín Ingibjörg Magnúsdóttir; Malin C. Lagerström; George H. Caughey; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pain; itch; CGRP; TRPV1; mast cell; mast cell protease; mMCP4; mMCP6; CPA3; endothelin-1; compound 48 80; MRGPRX2; single-stranded oligonucleotide;

   Abstract : Pain and itch are diverse sensory modalities, transmitted by the somatosensory nervous system. Stimuli such as heat, cold, mechanical pain and itch can be transmitted by different neuronal populations, which show considerable overlap with regards to sensory activation. READ MORE

5. 3. Immunopathogenesis of schistosomiasis mansoni : Immunity and pathology in a primary and a secondary infection following chemotherapy in the mouse and the baboo models

   Author : Idle Omar Farah; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Baboon; BALB c mice; Chemotherapy; Cytokines; Fibrosis; Granuloma; Modulation; Pathology; Reinfection; Schistosoma mansoni; Th1; Th2; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Medicine; medicin;

   Abstract : This thesis describes a series of experiments aimed at elucidating the mechanisms ofimmunity and pathology elicited by both a primary infection and a reinfection exposure toSchistosoma mansoni following chemotherapy. The effects of a single large cercarial doseand a cumulatively equivalent dose, administered as multiple small doses are compared. READ MORE

6. 4. Mycobacterial infection: Immune evasion, host susceptibility and immunological markers of diagnostic importance

   Author : John Arko-Mensah; Carmen Fernandez; Francesco Dieli; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacteria; Mice; Toll-like receptors; interferon gamma; immunological markers; lung; respiratory tract; susceptibility; Immunology; Immunologi; immunologi; Immunology;

   Abstract : IIn the first study, we investigated the functional implications of prolonged TLR signalling on IFN-γ mediated killing of mycobacteria by murine macrophages in vitro. TLR2, but not TLR4 ligation interfered with IFN-γ mediated killing of mycobacteria in macrophages. READ MORE

7. 5. Helicobacter pylori infection in a mouse model: Development, optimization and inhibitory effects of antioxidants

   Author : Xin Wang; Avdelningen för medicinsk mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; virology; bacteriology; Microbiology; mice; Helicobacter pylori; gastritis; lymphoma; antioxidant; diet; Th1 and Th2; cytokines; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Abstract : Helicobacter pylori is a human pathogen strongly associated with chronic type B gastritis, peptic ulcer disease, gastric cancer and MALT lymphoma. Our aims were to establish a mouse model of H. pylori infection, to study pathogenesis of gastritis and gastric cancer and to investigate new treatment strategies in this model. READ MORE