Search for dissertations about: "BK"

Showing result 1 - 5 of 31 swedish dissertations containing the word BK.

  2. 1. G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking

    Author : Caroline Sandén; Drug Target Discovery; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; receptor trafficking; B1 receptor; receptor oligomerization; estrogen; GPER1; G protein-coupled estrogen receptor 1; EP24.15; BK; bradykinin; B1R; B2R; B2 receptor; GPCR; receptor maturation;

    Abstract : The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. READ MORE

  4. 2. Polyomavirus infections in humans

    Author : Annika Lundstig; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Polyomaviruses; tumour virology; BK virus; neuroblastoma; maternal infection; Real Time PCR; enzyme immunoassay; seroprevalence; JC virus; SV40; virus like particles VLPs ; seroepidemiology; biobank; mesothelioma tissues; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : The human polyomaviruses BKV and JCV are endemic and infect > 70% of population worldwide. Primary infections occur during childhood and are largely subclinical. Following primary infection, both viruses persist as latent infections in the kidneys and B lymphocytes. READ MORE

  5. 3. Protein adaptability involved in self-assembled icosahedral capsids

    Author : Josefina Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : BK virus; lumazine synthase; virus-like particle; electron cryomicroscopy; quasiequivalence; assembly;

    Abstract : Interactions between viral coat proteins determine the size and shape of the virus capsid. Therefore, the plain closed shell of a spherical virus provides an excellent resource for studying and testing protein-protein interactions so as to reveal the properties that lead to symmetrical capsids or other shapes. READ MORE

  6. 4. Experimental methods to determine model parameters for failure modes of CFRP

    Author : Daniel Svensson; Ulf Stigh; Svante Alfredsson; Högskolan i Skövde; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; composite; delamination; compressive failure; energy release rate; cohesive modelling; Teknik; Technology;

    Abstract : The focus of this thesis is to develop methods to predict the damage response of Carbon Fibre Reinforced Polymers (CFRP). In the pursuit of reducing the manufacturing cost and weight of CFRP components, it is crucial to enable modelling of the non-linear response associated with various failure modes. READ MORE

  7. 5. Inflammation, kinins, and kinin receptors

    Author : Sara Bengtson; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Evidence is accumulating that the pathogenesis of many diseases is triggered by inappropriate inflammatory responses. These serious complications may occur when the tightly regulated inflammatory network is out of balance and it is now clear that this can eventually cause substantial harm to own cells and tissues. READ MORE