Search for dissertations about: "BMP4"
Showing result 1 - 5 of 13 swedish dissertations containing the word BMP4.
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1. Glioblastoma heterogeneity and plasticity : Investigating the roles of BMP4 and SOX2
Abstract : The malignant primary brain tumor glioblastoma has a dismal prognosis and is distinguished by its heterogeneous character. Current treatment with surgical resection, radiotherapy and adjuvant chemotherapy with the alkylating agent temozolomide does not provide a cure, but simply prolongs survival by a few months. READ MORE
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2. Bone Morphogenetic Protein 4 regulates white, beige and brown adipose tissue
Abstract : Obesity and its associated complications, including Type 2 diabetes, are increasing at an epidemic rate globally. Adipose tissue exerts different functions and is central in energy homeostasis, and it consists of white, beige or brown adipocytes. READ MORE
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3. WISP-2 - A Novel Adipokine Related to Obesity and Insulin resistance
Abstract : Type 2 diabetes mellitus (T2D) is increasing worldwide at an epidemic rate and is expected to reach 592 million inflicted individuals by 2035 as compared to 382 million in 2013. Obesity is a major risk factor for insulin resistance, defined as an impaired cellular effect of insulin, and this precedes the development of T2D. READ MORE
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4. Human iris characteristics as biomarkers for personality
Abstract : This dissertation explains why behavioral genetic research can be better informed by using characteristics in the human iris as biomarkers for personality, and is divided into five parts. Part I gives an introduction to the classical twin method and an overview of the findings that have led most developmental researchers to recognize that the normal variation of personality depends on a complex interplay between genetic and environmental factors. READ MORE
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5. From stem cells to neurons : a BMPy ride
Abstract : Pinpointing the mechanisms behind the formation of the vertebrate development has been an intriguing and challenging task for researchers for several decades. In the 1980s two independent groups managed to isolate cells from the inner cell mass of a mouse blastocyst and to culture and expand them in vitro, while maintaining their pluripotency. READ MORE