Search for dissertations about: "BONE and LIVER"

Showing result 1 - 5 of 91 swedish dissertations containing the words BONE and LIVER.

2. 1. Effects of GH and liver-derived IGF-I on growth and metabolism

   Author : Klara Sjögren; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GH; IGF-I; Insulin; GHRH; Somatostatin; GHS; Body growth; Body composition; Liver; Bone mineral content; Bone mineral density.;

   Abstract : Growth hormone (GH) exerts major effects on body growth and metabolism. Insulin-like growth factor (IGF) is expressed in response to GH and is known to mediate many of the effects of GH. The largest expression of IGF is found in the liver although it is expressed in virtually every tissue of the body. READ MORE

4. 2. Molecular and physiological functions of LRIG proteins and netrin-1 in health and disease

   Author : Carl Herdenberg; Håkan Hedman; Richard Palmqvist; Maréne Landström; Aristidis Moustakas; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LRIG; Netrin-1; LRIG1; LRIG2; LRIG3; Type 2 diabetes; Oncology; onkologi;

   Abstract : The leucine-rich repeats and immunoglobulin-like domains (LRIG) gene family has three members, LRIG1, LRIG2, and LRIG3, that encode three structurally similar transmembrane proteins. LRIG1 is a receptor tyrosine kinase regulator, tumor suppressor, and stem cell marker in the skin, intestine, and brain. READ MORE

5. 3. Human intestinal alkaline phosphatase : tissue expression and serum levels

   Author : Ulla Domar; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Human alkaline phosphatase; intestinal alkaline phosphatase; blood; blood group; lipid; monoclonal antibody; immunohistochemistry; liver; kidney; pancreas; liver disease; inflammatory bowel disease;

   Abstract : Human alkaline phosphatase (ALP) comprises four isozymes, viz liver/bone/ kidney or tissue unspecific (AP), intestinal (LAP), placental (PLAP) and germ cell or PLAP-like alkaline phosphatase, with their main expression in specific tissues as indicated by their names. The isozymes are coded by different genes, but they are closely related, with more than 50% amino acid sequence homologies. READ MORE

6. 4. Cancer imaging and image analysis methods in whole-body MRI and PET/MRI

   Author : Therese Sjöholm; Joel Kullberg; Filip Malmberg; Robin Strand; Håkan Ahlström; Einar Heiberg Brandt; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; magnetic resonance imaging; diffusion weighted imaging; positron emission tomography; whole-body imaging; normal atlas; CAR T-cell therapy; lymphoma; medical image analysis; Computerized Image Processing; Datoriserad bildbehandling;

   Abstract : Diagnostic medical imaging techniques such as magnetic resonance imaging (MRI) and positron emission tomography (PET) can provide structural and functional assessments of the whole body. This has great value for potentially systemic diseases such as cancer. READ MORE

7. 5. Regulation of Hematopoietic Stem and Progenitor Cells by Bone Marrow Niche Components

   Author : Hong Qian; Stamcellscentrum (SCC); []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stem cell; Hematologi; extracellular fluids; Haematology; bone marrow; Hematopoiesis; extracellulära vätskor;

   Abstract : Throughout the lifespan of an individual, enormous numbers of mature blood cells are generated by hematopoietic stem cells (HSCs) in the bone marrow (BM). The HSC is a cell that can self-renew to maintain the HSC pool and differentiate into all types of mature blood cells. READ MORE