Search for dissertations about: "BRCA1"
Showing result 16 - 20 of 57 swedish dissertations containing the word BRCA1.
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16. Hereditary breast/ovarian cancer : implementation of BRCA1 and BRCA2 testing
Abstract : Breast cancer is the most common malignancy among women in the western world. Most cases are sporadic but in 5 to 10 % an inherited genetic mutation is the main cause of the disease. READ MORE
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17. Hereditary Ovarian Cancer mutation frequencies and genetic profiles
Abstract : Ovarian cancer is a leading cause of gynecological cancer death and in Sweden nearly 700 cases are diagnosed annually. Ovarian cancer has one of the highest frequencies of hereditary cancer. READ MORE
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18. Breast cancer in young women. Aspects of heredity and contralateral disease
Abstract : Breast cancer is the most commonly diagnosed cancer among women in Sweden, as well as worldwide. In Sweden, 8,288 women were diagnosed with invasive breast cancer in 2019, out of whom approximately 1.5% were younger than 35 years of age. READ MORE
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19. Treatment of BRCA1/2-associated breast cancer and identification of mutation carriers among breast cancer patients
Abstract : The general aim of the research presented in this thesis was to contribute to the understanding of how breast cancer patients with germline BRCA1/2 mutations should be treated medically and surgically, and furthermore, to characterize the limitations and strengths of different procedures for BRCA testing. In Paper I, the long-term prognosis was assessed in a cohort of early-onset breast cancer patients (n = 221). READ MORE
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20. Molecular studies in breast cancer susceptibility genes
Abstract : Breast cancer is the most common malignancy among women, with a cumulative risk of approximately 12% by the age of 85. Of the breast cancer cases, 5-10% are hereditary. READ MORE