Search for dissertations about: "Bacillus anthracis"

Showing result 1 - 5 of 8 swedish dissertations containing the words Bacillus anthracis.

  2. 1. Using genomics to improve Bacillus anthracis diagnostics and outbreak investigations

    Author : Joakim Ågren; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The bacterium Bacillus anthracis causes the disease anthrax, primarily in herbivores but many mammals are susceptible to the disease. Its infective form is as a dormant spore that can lie in the soil for decades. READ MORE

  4. 2. Assesing performance of PCR analysis using Bayesian modelling

    Author : Ronny Hedell; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Bayesian; Hierarchical model; PCR; Low-template DNA; Bacillus anthracis; Sensitivity; Forensic science; Forensic science;

    Abstract : Different analytical methods are available to analyse the DNA samples from crime scenes or to screen samples for the presence of some target bacterium. For this purpose a method known as Polymerase Chain Reaction (PCR) can often be used. READ MORE

  5. 3. Bayesian inference for detection problems in biology

    Author : Ronny Hedell; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; PCR; Bayesian inference; Forensic DNA analysis; Syndromic surveillance; Bacillus anthracis; Markov chain Monte Carlo; Allele dropout; Bacillus anthracis;

    Abstract : This thesis is about different kinds of detection problems in biology: detection of DNA sequences in crime scene samples, detection of harmful bacteria in feed and food stuff and detection of epidemical diseases in animal populations. In each case, biological data is produced or collected in order to determine which DNA sequences, bacteria types or diseases are present, if any. READ MORE

  6. 4. Bacterial thioredoxin systems as potential drug targets in novel antimicrobial therapies

    Author : Tomas N Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Antimicrobial resistance is a big problem in modern medicine. One of the key components in the combat is the characterization of novel drug targets and the development of new classes of compounds targeting them. READ MORE

  7. 5. Structural basis for metalloprotein catalysis : Characterization of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase PgsA1 and Bacillus anthracis ribonucleotide reductase R2

    Author : Kristīne Grāve; Martin Högbom; Susanna Törnroth-Horsefield; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Abstract : About a third of all proteins need to associate with a particular metal ion or metallo-inorganic cofactor to function. This interplay expands the catalytic repertoire of enzymes and reflects the adaption of these catalytic macromolecules to the environments they have evolved in. READ MORE