Search for dissertations about: "Bacteria"

Showing result 1 - 5 of 2024 swedish dissertations containing the word Bacteria.

  1. 1. Disarming bacteria : a structure-based approach to design an anti-virulence drug against Listeria monocytogenes

    Author : Melanie Oelker; A. Elisabeth Sauer-Eriksson; Fredrik Almqvist; Karina Persson; Tiziano Tuccinardi; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antibiotic resistances; anti-virulence drug; Listeria monocytogenes; virulence regulation; PrfA; structure-based drug design; ring-fused 2-pyridones; allosteric regulation; Biochemistry; biokemi; medicinal chemistry; läkemedelskemi; molekylär cellbiologi; molecular cell biology; medicinsk biokemi; Medical Biochemistry; molekylärbiologi; Molecular Biology;

    Abstract : Antibiotic resistances are one of the biggest threats to global health and if we don’t change our behavior and way of using antibiotics we will end up in a ‘post-antibiotic era’, in which common infections and minor injuries can once kill again and up to 10 million deaths per year may occur by 2050. Therefore, there is a high need for new anti-bacterial drugs, especially of alternatives to existing antibiotics with already described resistances. READ MORE

  2. 2. Host-bacteria interactions : Host cell responses and bacterial pathogenesis

    Author : Nele de Klerk; Ann-Beth Jonsson; Teresa Frisan; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Host-bacteria interaction; Helicobacter pylori; Neisseria gonorrhoeae; Lactobacillus; Epithelial cells; Macrophages; EGR1; Amphiregulin; SabA; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Helicobacter pylori colonizes the human stomach, where it causes gastritis that may develop into peptic ulcer disease or cancer when left untreated. Neisseria gonorrhoeae colonizes the urogenital tract and causes the sexually transmitted disease gonorrhea. READ MORE

  3. 3. Dynamic Organization of Molecular Machines in Bacteria

    Author : Bhupender Singh; Santanu Dasgupta; Leif A. Kirsebom; Don G. Ennis; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molecular machines; bacteria; cell cycle; ribosome; replisome; divisome; spore; E. coli; H. pylori; Mycobacteria; Microbiology; Mikrobiologi; Mikrobiologi; Microbiology;

    Abstract : Bacterial cells were once treated as membrane-enclosed bags of cytoplasm: a homogeneous, undifferentiated suspension in which polymers (proteins, nucleic acids, etc.) and small molecules diffused freely to interact with each other. READ MORE

  4. 4. Environmental filtering of bacteria in low productivity habitats

    Author : Inga Richert; Stefan Bertilsson; Annelie Wendeberg; Lise Øvreås; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bacteria; environmental filtering; diversity; ecosystem service; hydrocarbon utilization; Southern Ocean; sediment; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Microbes fulfill important ecosystem functions by contributing as drivers of global nutrient cycles. Their distribution patterns are mainly controlled by environmental heterogeneities. So far, little is known about the mode of action of particular environmental drivers on the microbiota, particularly in low productivity habitats. READ MORE

  5. 5. Studies on Polysaccharides from some Gram-Negative Bacteria

    Author : Kurt Samuelsson; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bacteria; chemical methods; food infections; polysaccharides; salmonella; Information Systems; Informatik;

    Abstract : In this survey structural studies on some polysaccharides isolated from the families of Enterobachteriaceae (Klebsiella and Salmonella) and Parvobacteriaceae (Yersinia) will be discussed. The occurence of some rare or not earlier reported deoxysugars is demonstrated, namely, 6-deoxy-D-manno-heptose, 3-deoxy-L-glycero-pentulosonic acid and five of the isomers of 3,6-dideoxy-hexoses. READ MORE