Search for dissertations about: "Bacterial RNA polymerase"

Showing result 1 - 5 of 19 swedish dissertations containing the words Bacterial RNA polymerase.

  2. 1. Deciphering control of Mechano-Transcription Activators of σ54-RNA polymerase

    Author : Henrik Seibt; Victoria Shingler; Uwe H. Sauer; Ray Dixon; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Transcriptional regulation; P. putida; V. cholerae; AAA ; bEBP; B-linker; DmpR; Phenol catabolism; VCA0117; Type VI secretion; molekylärbiologi; Molecular Biology;

    Abstract : To survive and proliferate, bacteria have to respond to a plethora of fluctuating signals within their habitats. Transcriptional control is one crucial entry point for such signal-responsive adaption responses. READ MORE

  4. 2. Bacterial viruses targeting multi-resistant Klebsiella pneumoniae and Escherichia coli

    Author : Harald Eriksson; Anders Nilsson; Elisabeth Haggård-Ljungquist; Klas Flärdh; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bacterial viruses; Bacteriophage; Phage; Phage therapy; multi-resistant bacteria; Klebsiella pneumoniae; molekylärgenetik; Molecular Genetics;

    Abstract : The global increase in antibiotic resistance levels in bacteria is a growing concern to our society and highlights the need for alternative strategies to combat bacterial infections. Bacterial viruses (phages) are the natural predators of bacteria and are as diverse as their hosts, but our understanding of them is limited. READ MORE

  5. 3. New insights into the role of ppGpp and DksA through their effect on transcriptional regulation of housekeeping and colonization related genes of Escherichia coli

    Author : Anna Åberg; Carlos Balsalobre; Anne Farewell; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Escherichia coli; type 1 fimbriae; fimB; phase variation; transcription; global gene regualtion; ppGpp; DksA; gre-factors; RNA polymerase; Medical microbiology; Medicinsk mikrobiologi;

    Abstract : Bacteria have the ability to sense different environmental signals. When an environmental stress is detected, bacteria rapidly adjust their gene expression profile to be able to survive and thrive. READ MORE

  6. 4. Biased Evolution : Causes and Consequences

    Author : Gerrit Brandis; Diarmaid Hughes; Erik Böttger; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Evolution; Codon usage bias; Post-transcriptional regulation; Recombination; Inversion; EF-Tu; Frameshift suppression; Antibiotic resistance; Rifampicin; Ciprofloxacin; Compensatory evolution; Drug efflux; RNA polymerase; DNA gyrase; Mikrobiologi; Microbiology;

    Abstract : In evolution alternative genetic trajectories can potentially lead to similar phenotypic outcomes. However, certain trajectories are preferred over others. These preferences bias the genomes of living organisms and the underlying processes can be observed in ongoing evolution. READ MORE

  7. 5. The Role of the Escherichia coli RNA Polymerase β´Jaw in Transcription

    Author : Josefine Ederth; Leif A Isaksson; Anne Farewell; Stockholms universitet; []
    Keywords : mikrobiologi;

    Abstract : Transcription, the central step in gene expression and regulation, is carried out by the DNA-dependent RNA polymerase (RNAP). Bacterial RNAP is a complex molecular machine in which the network of interacting parts and their movements, including contacts to nascent RNA and the DNA template, are at best partially understood. READ MORE