Search for dissertations about: "Bakteriologi"
Showing result 6 - 10 of 184 swedish dissertations containing the word Bakteriologi.
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6. Reactive oxygen and nitrogen in host defence against Francisella tularensis
Abstract : Francisella tularensis, the causative agent of tularemia, is a potent human and animal pathogen. Initially upon infection of the host, intramacrophage proliferation of F. tularensis occurs but after activation of the acquired host immunity, the phagocytes become activated to kill the bacterium. In my thesis, I focused on mechanisms utilized by F. READ MORE
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7. Characterization of the attenuated Francisella tularensis strain FSC043 : with special focus on the gene pdpC
Abstract : Francisella tularensis is a highly infective, intracellular bacterium. It is capable of infecting a wide range of mammals and causes the disease tularemia in humans. As a result of its high infectivity there have been a lot of efforts made to create a generally available vaccine against this pathogen. READ MORE
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8. Mechanisms of the intracellular survival of Francisella tularensis
Abstract : Francisella tularensis is a gram-negative, highly virulent, intracellular bacterium which causes the zoonotic disease tularemia. The subspecies tularensis and holarctica are clinically important, and the former is the more virulent. The intracellular lifestyle of F. READ MORE
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9. Effects of Francisella tularensis infection on macrophage intracellular signaling
Abstract : Microbes contain a number of structural components, also known as pathogen associated molecular patterns (PAMP), which can be recognized by the host defense system. The PAMP serve as ligands for Toll-like receptors (TLR) expressed on phagocytic cells. READ MORE
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10. Optimisation of diagnostic PCR a study of PCR inhibitors in blood and sample pretreatment
Abstract : PCR is widely employed as a rapid, sensitive and specific molecular diagnostic technique in clinical diagnosis, environmental investigations and for monitoring biotechnical processes. However, the full potential of diagnostic PCR is limited, in part, by the presence of PCR-inhibitory substances in biological samples. READ MORE