Search for dissertations about: "Barbara Hjelm"

Found 1 swedish dissertation containing the words Barbara Hjelm.

  1. 1. Epitope mapping of antibodies towards human protein targets

    Author : Barbara Hjelm; Mathias Uhlén; Larry Gold; KTH; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; antibody; antibody validation; biomarker; epitope mapping; peptide array; proteomics; RBM3; staphylococcal surface display;

    Abstract : This thesis, based on five research papers, presents results from development and evaluation ofmethods for identifying the interaction site of antibodies on their antigens and the functional investigation of these in different assays. As antibodies have proven to be invaluable tools in diagnostics, therapy and basic research, the demand of characterizing these binding molecules has increased. READ MORE