Search for dissertations about: "Barrett’s esophagus"

Showing result 1 - 5 of 12 swedish dissertations containing the words Barrett’s esophagus.

2. 1. The Columnar Lined Esophagus. Pathophysiological and Clinical Aspects

   Author : Stefan Öberg; Lund Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intestinal metaplasia; Barrett s esophagus; Esophageal columnar metaplasia; Metaplasia; Pathophysiology; Gastroesophageal reflux disease; Esophagus; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

   Abstract : There is a persisting controversy concerning the definition, etiology and pathogenesis of Barrett's esophagus. The dramatic and parallel increase in the incidence of esophageal and junctional adenocarcinoma over the past decades justifies an evaluation of the pathophysiology of premalignant metaplastic changes of the esophagus and the gastroesophageal junction. READ MORE

4. 2. Aspects on endoscopic characterization and clinical management of Barrett's esophagus

   Author : Francisco Baldaque Silva; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Barrett’s esophagus;

   Abstract : Barrett's esophagus (BE) is considered to result from prolonged gastroesophageal reflux and is the only known precursor of esophageal adenocarcinoma. The clinical management of BE patients aims to control esophageal reflux to reduce mucosal injury and neoplastic progression, and to detect early neoplastic lesions in Barrett’s mucosa, suitable for curative endoscopic treatment. READ MORE

5. 3. p53 and neoplastic progression in Barrett's esophagus

   Author : Stig Ramel; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Barrett s esophagus; neoplastic progression; flow cytometry; p53 gene; p53protein; 17p allelic loss; p53 mutations; S phase fractions; aneuploidy; SV 40 large T antigen; elastase-SV 40 T antigen transgenic mice.;

   Abstract : Barrett's esophagus is a condition in which the normal squamous epithelium is replaced by columnar epithelium as a response to acid reflux. It develops as a complication in 10-20% of patients with gastroesophageal reflux disease. READ MORE

6. 4. Barrett's esophagus and the risk of adenocarcinoma

   Author : Dag Holmberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Barrett’s esophagus is the precursor lesion of esophageal adenocarcinoma, a tumor with increasing incidence and poor prognosis. The overall aim of the thesis was to assess risk and prognosis in patients with Barrett’s esophagus and esophageal adenocarcinoma. READ MORE

7. 5. Gastroesophageal reflux disease - complications and prognostic aspects

   Author : Dan Falkenback; Lund Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastroesophageal reflux disease; Barrett s esophagus; natural course; GERD; Adenocarcinoma; prognosis; biomarkers;

   Abstract : This thesis investigates several aspects on gastroesophageal reflux disease (GERD) and associated complications as Barrett’s esophagus and esophageal adenocarcinoma. I. To clarify the natural course of GERD, a pH-metry verified cohort was re-evaluated after 20 years. The course of GERD may well be progressive. READ MORE