Search for dissertations about: "Basement membrane"

Showing result 1 - 5 of 86 swedish dissertations containing the words Basement membrane.

  2. 1. Basement membrane collagens in pancreatic cancer : novel stroma-derived tumor markers and regulators of cancer cell growth

    Author : Daniel Öhlund; Malin Sund; Peter Naredi; Matthias Löhr; Umeå universitet; []
    Keywords : Pancreatic cancer; tumor marker; basement membrane; type IV collagen; type XVIII collagen; matrix metalloproteinase; integrin; autocrine loop; tumor stroma; kirurgi; Surgery;

    Abstract : Background: Among the common malignancies, pancreatic cancer has the shortest long-term survival. The aggressive, rapid, and infiltrative growth pattern of pancreatic cancer, together with the lack of specific symptoms, often leads to late diagnosis. READ MORE

  4. 2. Basement membrane components and their receptors in organogenesis

    Author : Katriina Salmivirta; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Basement membrane; laminin; collagen type IV; nidogen; integrin; morphogenesis; organogenesis; tooth; salivary gland; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; fysiologi; Physiology;

    Abstract : During embryogenesis organs are formed from epithelial and mesenchymal tissues. Organogenesis is dependent on interactions between epithelium and mesenchyme. Specialized extracellular matrices, basement membranes, located between the two tissue types play a crucial role in mediating the interactions. READ MORE

  5. 3. Basement membrane components in the chondrocyte extracellular matrix

    Author : Alexander Kvist; Lunds universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skelett; rheumatology locomotion; nidogen; chondroitin sulfate; collagen assembly; Skeleton; muscle system; type IV collagen; laminin; perlecan; basement membranes; ECM; chondrcytes; muskelsystem; reumatologi;

    Abstract : The extracellular matrix (ECM) is a network of macromolecules which, together with cells, forms the various tissues of all metazoan organisms. Cartilage, in contrast to most other tissues, contains relatively few cells in proportion to the volume occupied by ECM. READ MORE

  6. 4. Gene expression studies of pregastrulation development: the basement membrane is essential for cell differentiation

    Author : Mikael Åkerlund; Muskelbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscular dystrophy; development; Basement membrane; laminin; stem cells; FGF;

    Abstract : Basement membranes (BMs) are sheet-like structures of extracellular matrix. They act as a supporting structure but can also significantly influence cellular behavior in development, tissue homeostasis and disease. Laminins, a major BM component, are multidomain proteins, consisting of three polypeptide chains (α, β and γ). READ MORE

  7. 5. Basement membrane heparan sulfate in atherogenesis and intimal hyperplasia

    Author : Karin Tran Lundmark; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cardiovascular disease due to atherosclerosis has become the leading cause of mortality in the world. Atherosclerosis is a progressive disease characterized by the accumulation of lipids, inflammatory cells, smooth muscle cells (SMCs) and extracellular matrix in the wall of large and medium-sized arteries. READ MORE