Search for dissertations about: "Behavioural deficits"

Showing result 1 - 5 of 44 swedish dissertations containing the words Behavioural deficits.

  2. 1. MPTP-induced behavioural deficits in mice : validity and utility of a model of Parkinsonism

    Author : Anders Fredriksson; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  4. 2. Schizophrenia and Nitric Oxide: Deficits in Information Processing Invetigated in Animal Models

    Author : Daniel Klamer; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phencyclidine – nitric oxide – prepulse inhibition – habituation – acoustic startle – cAMP – in vivo microdialysis – NMDA receptor – rat – mouse – schizophrenia;

    Abstract : Rationale: Schizophrenia-like symptoms can be induced in humans by phencyclidine (PCP), a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor. Schizophrenic patients and PCP-treated animals display deficits in pre-attentive information processing, as assessed by e.g. prepulse inhibition of the acoustic startle response. READ MORE

  5. 3. Computerized rehabilitation for cognitive deficits after central nervous system malaria in Ugandan children

    Author : Paul Bangirana; Karolinska Institutet; Karolinska Institutet; []
    Keywords : CNS malaria;

    Abstract : Background: Malaria infecting the central nervous system (CNS) affects over 575,000 children annually in sub-Saharan Africa leading to cognitive deficits. The effect of this form of malaria on everyday behaviour and academic achievement has not been investigated in Uganda. READ MORE

  6. 4. Anatomical, neurochemical and behavioural consequences of immunotoxin lesions of the basal forebrain cholinergic system

    Author : Giampiero Leanza; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural transplantation; reinnervation; axon growth; functional sparing; memory; learning; cortex; hippocampus; immunolesion; acetylcholine; basal forebrain; rat; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; Physiology; Fysiologi;

    Abstract : The cholinergic hypothesis of geriatric memory dysfunction suggests that the learning and memory deficits representing the cardinal symptoms of dementia in the aged and in patients suffering from Alzheimer's disease may be attributable to a decline in the function of the cholinergic projection systems of the basal forebrain. Although many studies have addressed the issue of a causal relationship between cholinergic hypofunction and cognitive disturbance, analyses of the functional role of the basal forebrain cholinergic neuronal systems in the brain have so far been hampered by the lack of an efficient and specific cholinergic neurotoxin. READ MORE

  7. 5. Movement pattern analysis of hypoglutamatergic mice. A model for cognitive deficits of schizophrenia and autism?

    Author : Marie Nilsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; schizophrenia; autism; cognition; movement pattern; video tracking; MK-801; mice;

    Abstract : Schizophrenia and autism are two severe neuropsychiatric disorders that are associated withprofound cognitive disturbances which considerably contribute to the long-term morbidity andthe decreased ability to function in the society. Currently used therapies do not reach the corecognitive disturbances to a satisfactory extent. READ MORE