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Showing result 1 - 5 of 62 swedish dissertations matching the above criteria.

2. 1. Directed Evolution of Glutathione Transferases with Altered Substrate Selectivity Profiles : A Laboratory Evolution Study Shedding Light on the Multidimensional Nature of Epistasis

   Author : Wei Zhang; Bengt Mannervik; Bengt-Harald Jonsson; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; glutathione transferase; azathioprine; directed evolution; semi-rational design; catalytic mechanism; saturation mutagenesis; reduced amino acid alphabets; molecular docking; protein evolution; multivariate data analysis; epistasis; fitness landscape; evolutionary trajectories; Biochemistry; Biokemi; Biokemi; Biochemistry;

   Abstract : Directed evolution is generally regarded as a useful approach in protein engineering. By subjecting members of a mutant library to the power of Darwinian evolution, desired protein properties are obtained. Numerous reports have appeared in the literature showing the success of tailoring proteins for various applications by this method. READ MORE

4. 2. Switched-current circuits : from building blocks to mixed analog-digital systems

   Author : Bengt Jonsson; KTH; []
   Keywords : ;

   Abstract : .... READ MORE

5. 3. Charge Transport in Transition Metal Oxide Thin Films and Electrochromic Devices

   Author : AnnaKarin Jonsson; Bengt-Erik Mellander; Uppsala universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Engineering physics; Teknisk fysik; Engineering physics; Teknisk fysik; Solid State Physics; Fasta tillståndets fysik;

   Abstract : Thin film devices for windows, mirrors, space applications and other purposes, have become an essential part of modern technology. A great advantage with a thin film device is the small amount of material used and the compact volume of the device. READ MORE

6. 4. Seven Years That Shook Economic and Social Thinking : Reflections on the Revolution in Communist Economics 1985-1991

   Author : Bengt Svensson; Thomas Jonter; Ulf Jonsson; Ronny Pettersson; Ann-Mari Sätre Åhlander; Stockholms universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; perestroíka; planned economy; labour theory of value; socialist market; market socialism; market economics; shock therapy; gradual transition; Economic history; Ekonomisk historia; Economic History; ekonomisk historia;

   Abstract : The main theme of this study is to analyze the Soviet economic theoretical debate in the period 1985 – 1991. This period of reconstruction gave possibilities of a more free debate. READ MORE

7. 5. Atherosclerotic cardiovascular disease in rheumatoid arthritis : aspects of pathogenesis and risk

   Author : Bengt Wahlin; Solveig Wållberg-Jonsson; Anna Södergren; Anders Bengtsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; inflammation; atherosclerosis; cardiovascular disease; risk estimation; cytomegalovirus; T-cells; bone turnover; osteoprotegerin; osteocalcin; Medicine; medicin;

   Abstract : Patients with rheumatoid arthritis (RA) have an increased prevalence and severity of atherosclerosis, and a corresponding increased risk of cardiovascular disease. The mechanisms causing this are not well elucidated, but both traditional cardiovascular risk factors and RA-associated factors have been associated with atherosclerosis and increased risk of cardiovascular events in patients with RA. READ MORE