Search for dissertations about: "Bengt Westermark"
Showing result 1 - 5 of 10 swedish dissertations containing the words Bengt Westermark.
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1. Growth control of normal and neoplastic human glia-like cells in culture
Abstract : .... READ MORE
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2. Investigations of Proneural Glioblastoma to Identify Novel Therapeutic Targets
Abstract : Malignant glioma is a highly lethal and destructive disease with no proper cure. We have investigated some of the hallmarks of cancer in connection to glioma and found ways to disrupt these and prevent tumor growth. The work is done within the context of a glioma subtype distinguished by activation of PDGF signaling termed the proneural subtype. READ MORE
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3. Molecular and Cellular Complexity of Glioma : Highlights on the Double-Edged-Sword of Infiltration Versus Proliferation and the Involvement of T Cells
Abstract : Glioblastoma multiforme (GBM), the most common and malignant brain tumor, is characterized by high molecular and cellular heterogeneity within and among tumors. Parameters such as invasive growth, infiltration of immune cells and endothelial proliferation contribute in a systemic manner to maintain the malignancy. READ MORE
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4. Glioblastoma heterogeneity and plasticity : Investigating the roles of BMP4 and SOX2
Abstract : The malignant primary brain tumor glioblastoma has a dismal prognosis and is distinguished by its heterogeneous character. Current treatment with surgical resection, radiotherapy and adjuvant chemotherapy with the alkylating agent temozolomide does not provide a cure, but simply prolongs survival by a few months. READ MORE
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5. Roles of PDGF for Neural Stem Cells
Abstract : Stem cells are endowed with unique qualities: they can both self-renew and give rise to new mature cell types. Central nervous system (CNS) stem cells can give rise to neurons and glia. READ MORE