Search for dissertations about: "Bengt Widegren"

Found 2 swedish dissertations containing the words Bengt Widegren.

  1. 1. Studies on Human Endogenous Retroviruses (HERVs) with Special Focus on ERV3

    Author : Ann-Catrin Andersson; Bengt Widegren; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; human endogenous retroviruses; HERV; ERV3; expression; in situ hybridisation; real-time PCR; U-937; retinoic acid.; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Human endogenous retroviruses (HERVs) represent approximately 7% of the human genome. This investigation was focused on one particular HERV, ERV3, with the main purpose of characterising its gene expression patterns and genomic distribution of ERV3-like sequences. READ MORE

  2. 2. Towards Immunotherapy of Midgut Carcinoid Tumors

    Author : Sofia Vikman; Thomas Tötterman; Valeria Giandomenico; Bengt Widegren; Uppsala universitet; []
    Keywords : Immunology; midgut carcinoid; gene expression; immunotherapy; tumor antigen; VMAT-1; T cell; HLA-A*0201-binding peptide; IFNγ; regulatory T cell; Immunologi;

    Abstract : Classical midgut carcinoids belong to neuroendocrine tumors of the gastroenteropancreatic tract (GEP-NETs) and are associated with serotonin overproduction. The term midgut is derived from the tumors’ embryological site of origin: enterochromaffin cells in the lower jejunum, ileum, caecum and the ascending colon. READ MORE