Search for dissertations about: "Benign breast disease"

Showing result 1 - 5 of 13 swedish dissertations containing the words Benign breast disease.

2. 1. Studies of gene fusions and copy number alterations in salivary and adnexal neoplasms

   Author : Marta Persson; Göteborgs universitet; []
   Keywords : cancer genetics; fusion oncogenes; chromosome translocation; MYB; NFIB; CRTC1; MAML2; salivary gland; breast; adenoid cystic carcinoma; mucoepidermoid carcinoma; hidradenoma;

   Abstract : Cancer is a genetic disease caused by the accumulation of genetic changes such as mutations and chromosomal rearrangements. An increasing number of genetic studies of both hematological and solid neoplasms have shown that recurrent chromosome translocations often result in fusion oncogenes. READ MORE

4. 2. On ionising radiation and breast cancer risk

   Author : Anders Mattsson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ionising radiation; breast cancer induction; cancer induction; risk models; risk modification; pooled analysis; mammmographic screening; gained lost years of life;

   Abstract : Background: It is well known that exposure to ionising radiation increases the risk for breast cancer occurrence. However, better understanding of breast cancer risks in terms of dose-response relationships formulated according to radiobiological target theories, age-at-exposure patterns and temporal dependence are important for the understanding of the underlying biological mechanism of radiation carcinogenesis as well as for the concern about possible risks associated with the very low doses received from routine mammographic screening. READ MORE

5. 3. Dynamic magnetic resonance imaging of the breast : imaging features for diagnosis and prognosis of breast cancer

   Author : Botond K Szabo; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Breast neoplasm; magnetic resonance imaging; prognostic factors; survival analysis; image segmentation; artificial neural networks;

   Abstract : The general aim of the present thesis was to identify and study dynamic contrast-enhanced magnetic resonance imaging (CE-MRI) features that contribute to the diagnosis and may help in predicting prognosis in breast cancer. Study I studied the kinetic and morphological MR features and their diagnostic power were studied in a total of 92 women with 109 histopathologically verified breast lesions. READ MORE

6. 4. Epidemiological studies on breast cancer risk factors and screening

   Author : Xinhe Mao; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : This thesis aims to enhance cancer prevention by investigating the factors and outcomes associated with false-positive (FP) mammography recalls, as well as understanding the association between breast cancer risk factors of women and cancer risk among their relatives. Specifically, four studies were conducted using data from Swedish national registers, the Karolinska Mammography Project for Risk Prediction of Breast Cancer (KARMA) cohort, and the Linné-Bröst1 (Libro-1) cohort. READ MORE

7. 5. Hormone-related factors and breast cancer : studies of risk and prognosis

   Author : Lena Rosenberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Epidemiology; breast neoplasms; body mass index; hormone replacement therapy; reproductive history; ductal carcinoma; lobular carcinoma; tubular carcinoma; estrogen receptor; progesterone receptor; risk assessment; survival;

   Abstract : The main purpose of this thesis was to explore the influences of risk factors for breast cancer on breast cancer characteristics and survival. We evaluated the associations between number and timing of births and breast cancer-specific survival using data from the Swedish Cancer Register, the Swedish Cause of Death Register, and the Multi-Generation Register. READ MORE