Search for dissertations about: "Benzimidazoles"

Showing result 1 - 5 of 6 swedish dissertations containing the word Benzimidazoles.

  2. 1. Preclinical Characterization in vivo and in vitro of Novel Agents for Cancer Chemotherapy : Studies on Benomyl, Carbendazim, Cryptolepine and Acriflavine

    Author : Daniel Laryea; Peter Nygren; Moustapha Hassan; Uppsala universitet; []
    Keywords : Benzimidazoles; cryptolepine; acriflavine; cancer; high throughput screening; cytotoxic drug; gene expression;

    Abstract : Preclinical methods for the identification and characterization of molecules for development into new cancer drugs were investigated. Based on repurposing, i.e. READ MORE

  4. 2. Development of metal complexes for water oxidation

    Author : Bao-Lin Lee; Sascha Tiede; Stockholms universitet; []
    Keywords : ;

    Abstract : In the course of developing a water oxidation catalyst, five metal complexes have been synthesised, characterised and studied for catalytic activity. Three of them are dinuclear complexes (Ru, Co and Cu) of 2,6-bis[(2-hydroxybenzyl)-(2-pyridylmethyl)aminomethyl]-4-methylphenol (H3bbpmp). READ MORE

  5. 3. Development of metal complexes for water oxidation

    Author : Bao-Lin Lee; Björn Åkermark; Xiaodong Zou; Antoni Llobet; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; organisk kemi; Organic Chemistry;

    Abstract : In an artificial version of photosynthesis, sunlight and water are used to produce fuels. Our research focuses on the bottleneck in this process, the photooxidation of water. In the course of developing a water oxidation catalyst, a number of metal complexes have been synthesised, characterised, and studied for catalytic activity. READ MORE

  6. 4. Deradicalising Giardiasis Treatment

    Author : Sascha Krakovka; Staffan Svärd; Jon Jerlström-Hultqvist; Norbert Müller; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Giardia; encystation; antibiotic resistance; metronidazole; transcriptomics; proteomics; thymidine kinase;

    Abstract : Giardia intestinalis is a unicellular parasite causing the disease giardiasis. This disease is mostly prevalent in low resource settings, mandating low-cost treatment options. READ MORE

  7. 5. Mechanisms of activation of the aryl hydrocarbon receptor by novel inducers of the CYP1A1 gene

    Author : Maria Backlund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : AhR; omeprazole; primaquine; CYP1A1; ligand-independent activation; ligandbinding domain; protein tyrosine kinase; c-src kinase;

    Abstract : The aryl hydrocarbon receptor (AhR) functions as a ligand-activated transcription factor that is responsible for the activation of several response genes, of which the best characterised is the CYP1A1 gene. The prototype high affinity ligand for the AhR is the environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). READ MORE