Search for dissertations about: "Bile acid"
Showing result 11 - 15 of 117 swedish dissertations containing the words Bile acid.
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11. Hydrophobic interactions of serpins
Abstract : The proteins of the serpin family are primarily but not exclusively proteinase inhibitors, which share a common, similar structure. It is known that this structure undergoes major conformational changes upon cleavage in the serpin reactive site loop, and that these changes include rearrangements within the hydrophobic core of the molecule. READ MORE
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12. Modulation of bile acid and cholesterol metabolism in health and disease
Abstract : An increased level of plasma cholesterol is associated with premature development of atherosclerosis. It is therefore important to understand the regulation of plasma cholesterol. Stimulation of hepatic bile acid synthesis is a strategy to reduce plasma cholesterol. This partly occurs due to an induction of hepatic LDL receptors. READ MORE
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13. On the regulation of hepatic cholesterol and bile acid metabolism in gallstone patients
Abstract : The liver plays an important role in the regulation of cholesterol homeostasis, therefore also in the pathogenesis of arteriosclerosis and gallstone disease. The quantitatively most important way by which cholesterol is removed from the human body is via the bile, either as free cholesterol or after transformation to bile acids. READ MORE
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14. The interplay between bile acids and gut microbiota in metabolic and hepatobiliary disease
Abstract : The gut microbiota, a metabolic regulator, orchestrates the production of bioactive metabolites such as secondary bile acids. Growing evidence suggests that shifts in the gut microbiota composition are linked to metabolic and hepatobiliary disease. READ MORE
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15. Studies on cholesterol and bile acid metabolism in Chinese cholesterol gallstone patients
Abstract : Liver and intestine are important organs for the metabolism of cholesterol and bile acids in the body. Dysfunction in cholesterol and bile acid metabolism may lead to diseases such as cholesterol gallstone (GS) disease and atherosclerosis. READ MORE