Search for dissertations about: "Binding Sites"
Showing result 1 - 5 of 695 swedish dissertations containing the words Binding Sites.
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1. C4b-binding protein: Identification of binding sites and a possible function of the interaction with protein S
Abstract : The subject of this thesis is plasma protein C4b-binding protein (C4BP). C4BP is an important regulator of the classical pathway of the complement system, a cascade-like system comprised of over 35 proteins, which partakes in the defence against micro-organisms and is involved of clearance of immune-complexes and apoptotic cells. READ MORE
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2. Binding of drugs to human serum albumin : identification of specific binding sites and influence of some diseases
Abstract : .... READ MORE
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3. Protein structure prediction : Zinc-binding sites, one-dimensional structure and remote homology
Abstract : Predicting the three-dimensional (3D) structure of proteins is a central problem in biology. These computationally predicted 3D protein structures have been successfully applied in many fields of biomedicine, e.g. family assignments and drug discovery. READ MORE
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4. DNA Interactions with Chiral Polyaza-aromatic Ruthenium(II) Complexes
Abstract : The binding to DNA of a series of chiral ruthenium complexes is studied with optical spectroscopy techniques, including isotropic absorption, linear dichroism (LD) and emission anisotropy as well as steady-state and time-resolved luminescence. The thesis focuses on the ìlight-switchî complex [Ru(phen)2dppz]2+ which binds to DNA by intercalation and luminesces when bound to DNA but not in pure buffer solution (phen=1,10-phenanthroline; dppz=dipyrido[3,2-a:2',3'-c]phenazine). READ MORE
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5. Statistical models of TF/DNA interaction
Abstract : Gene expression is regulated in response to metabolic necessities and environmental changes throughout the life of a cell. A major part of this regulation is governed at the level of transcription, deciding whether messengers to specific genes are produced or not. READ MORE