Search for dissertations about: "Biochemistry towards Bioinformatics"

Showing result 16 - 20 of 41 swedish dissertations containing the words Biochemistry towards Bioinformatics.

  2. 16. Transmembrane Proteins and Protein Structure Prediction : What we can learn from Computational Methods

    Author : John Lamb; Arne Elofsson; Paolo Marcatili; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; contact prediction; transmembrane protein; topology prediction; machine learning; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : A protein’s 3D-structure is essential to understand how proteins function and interact and how biochemical processes proceed in organic life. Despite the advancement in experimental methods, it remains expensive and time-consuming to determine protein structure experimentally. READ MORE

  4. 17. Intrinsic disorder and tandem repeats - match made in evolution : Computational studies of molecular evolution

    Author : Oxana Lundström; Arne Elofsson; Liberles-Siltberg Jessica; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein evolution; intrinsically disordered proteins IDPs ; tandem repeats; short tandem repeats STRs ; genetic variation; orphan proteins; GC content; human STR variation; colorectal cancer; gene expression; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Abstract : Proteins are both the building blocks and workers of the cell, carrying out most of the important functions. For a long time, their structure has been regarded as the primary factor for their function, but intrinsically disordered proteins demonstrate an alternative to this paradigm. READ MORE

  5. 18. Host-parasite interactions in space and time

    Author : Franziska Hildebrandt; Johan Ankarklev; Volker T. Heussler; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Malaria; liver-stage infection; Toxoplasma; host-parasite interactions; spatial transcriptomics; single-cell omics; single-cell Dual-seq; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Unicellular parasites of the apicomplexan phylum have a considerable effect on global health and agriculture. Two prominent examples of this phylum include malaria causing parasites of the Plasmodium genus and the widely prevalent parasite Toxoplasma gondii. READ MORE

  6. 19. Structured Learning for Structural Bioinformatics : Applications of Deep Learning to Protein Structure Prediction

    Author : David Menéndez Hurtado; Arne Elofsson; Sergei Grudinin; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Proteins are the basic molecular machines of the cell, performing a broad range of tasks, from structural support to catalysisof chemical reactions. Their function is determined by their 3D structure, which in turn is dictated by the order of their components, the amino acids. READ MORE

  7. 20. Towards Reliable Gene Regulatory Network Inference

    Author : Daniel Morgan; Erik Sonnhammer; John Quackenbush; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; GRN; network inference; biological systems; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Phenotypic traits are now known to stem from the interplay between genetic variables across many if not every level of biology. The field of gene regulatory network (GRN) inference is concerned with understanding the regulatory interactions between genes in a cell, in order to build a model that captures the behaviour of the system. READ MORE