Search for dissertations about: "Biochemistry"
Showing result 1 - 5 of 2069 swedish dissertations containing the word Biochemistry.
-
1. Proteins of the Inter-α-inhibitor Family Biosynthesis, Plasma Clearance and Interaction with Extracellular Matrix Components
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Bikunin, a chondroitin sulfate-containing protein of 25 kDa, has protease inhibitory activity and occurs in the plasma in free and complexed form. In inter-α-inhibitor (IαI) and pre-a-inhibitor (PαI) it is covalently linked through its chondroitin sulfate (CS) chain to two or one other polypeptide of about 80 kDa – heavy chains 1 and 2 (H1, H2) and heavy chain 3 (H3) – respectively. READ MORE
-
2. On the Versatility of Microwave-Assisted Chemistry Exemplified by Applications in Medicinal Chemistry, Heterocyclic Chemistry and Biochemistry
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Today, the demand for speed in drug discovery is constantly increasing, particularly in the iterative processes of hit validation and expansion and lead optimization. Irradiation with microwaves (MWs) has been applied in the area of organic synthesis to accelerate chemical reactions and to facilitate the generation of new chemical entities since 1986. READ MORE
-
3. DNA precursor biosynthesis-allosteric regulation and medical applications
University dissertation from Umeå : Medicinsk kemi och biofysikAbstract : Ribonucleotide reductase (RNR) is a key enzyme for de novo dNTP biosynthesis. We have studied nucleotide-dependent oligomerization of the allosterically regulated mammalian RNR using a mass spectrometry–related technique called Gas-phase Electrophoretic Mobility Macromolecule Analysis (GEMMA). READ MORE
-
4. Two Types of Fibrils in ATTR Amyloidosis Implications for Clinical Phenotype and Treatment Outcome
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Systemic amyloidoses are a group of lethal diseases where proteins aggregate into fibrillar structures, called amyloid fibrils, that deposits throughout the body. Transthyretin (TTR) causes one type of amyloidosis, in which the aggregates mainly infiltrate nervous and cardiac tissue. READ MORE
-
5. Computational Modeling of the Structure, Function and Dynamics of Biomolecular Systems
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Proteins are a structurally diverse and functionally versatile class of biomolecules. They perform a variety of life-sustaining biological processes with utmost efficiency. A profound understanding of protein function requires knowledge of its structure. READ MORE
